Studies on Aminobenzothiazole and Derivatives: Part-2. Synthesis of Intermediates -Substituted Phenylthiourea using Ammonium Thiocyanate
International Journal of Pharmaceutical & Biological Archive, 2019; 10(3):226-231
6 Pages Posted: 25 Mar 2021
Date Written: September 15, 2019
Abstract
The substituted phenylthiourea is used as intermediate in different reactions because they play an important role in synthesizing the heterocyclic compounds. These reactions involve the synthesis of an intermediate phenylammonium chloride which is converted to substituted thiourea using ammonium thiocyanate. The final product formed, substituted phenylthiourea has potential to use as an intermediate in the synthesis of a building block for the heterocyclic compound, 2-aminobenzothiazole.
Keywords: Aminobenzothiazole and heterocyclic compound, building block, phenylammonium chloride, phenylthiourea
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