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The Epidemiology of Depressive Disorders and Service Use in China: Findings from the China Mental Health Survey

51 Pages Posted: 4 Mar 2021

See all articles by Jin Lu

Jin Lu

Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University

Xiufeng Xu

Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University

Yueqin Huang

Peking University - Institute of Mental Health

Tao Li

Sichuan University - West China Hospital

Chao Ma

Peking University - NHC Key Laboratory of Mental Health

Guangming Xu

Nankai University - Affiliated Tianjin Anding Hospital

Huifang Yin

Nankai University - Affiliated Tianjin Anding Hospital

Xiangdong Xu

The Fourth People's Hospital in Urumqi

Yanjuan Ma

The Fourth People's Hospital in Urumqi

Limin Wang

Chinese Center for Disease Control and Prevention (China CDC) - National Center for Chronic Non-Communicable Disease Control and Prevention

Zhengjing Huang

Chinese Center for Disease Control and Prevention (China CDC) - National Center for Chronic Non-Communicable Disease Control and Prevention

Yongping Yan

Department of Epidemiology, the Fourth Military Medical University

Bo Wang

Department of Epidemiology, the Fourth Military Medical University

Shui-yuan Xiao

Central South University - Department of Social Medicine and Health Management

Liang Zhou

Guangzhou Medical University - Affiliated Brain Hospital

Lingjiang Li

Central South University - Second Xiangya Hospital

Yan Zhang

Mental Health Institute, the Second Xiangya Hospital, Central South University

Hongguang Chen

Peking University - NHC Key Laboratory of Mental Health

Tingting Zhang

Peking University - NHC Key Laboratory of Mental Health

Jie Yan

Peking University - Institute of Social Science Survey - ISSS

Hua Ding

Peking University - Institute of Social Science Survey - ISSS

Yaqin Yu

Department of Epidemiology and Biostatistics, School of Public Health, Jilin University

Changgui Kou

Department of Epidemiology and Biostatistics, School of Public Health, Jilin University

Zonglin Shen

Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University

Linlin Jiang

Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Division of Prevention and Community Health

Zhizhong Wang

Zunyi Medical University

Xian Sun

Department of Epidemiology and Statistics, School of Public Health, Ningxia Medical University

Yifeng Xu

Shanghai Jiao Tong University (SJTU) - Shanghai Clinical Research Center for Mental Health

Yanling He

Shanghai Jiao Tong University (SJTU) - Shanghai Mental Health Center

Wan Jun Guo

Zhejiang University - Affiliated Mental Health Center

Lijun Jiang

Huazhong University of Science and Technology - Department of Hematology

Shengyan Li

Third People's Hospital of Qinghai Province

Wen Pan

Suzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University

Yue Wu

Nanjing Medical University - Wuxi Mental Health Center

Guohua Li

Chifeng Anding Hospital

Fujun Jia

Guangdong Academy of Medical Sciences - Guangdong Mental Health Center

Jianfei Shi

Department of Psychiatry, Hangzhou Seventh People’s Hospital

Zhongxia Shen

Third People’s Hospital of Huzhou

Ning Zhang

Nanjing Medical University - Affiliated Brain Hospital

More...

Abstract

Background: In China, depressive disorders have been estimated to be the second leading cause of years lived with disability (YLDs). However, nationally representative epidemiological data for depressive disorders, in particular depressed adults’ mental health services use, are still unavailable in China. The present study is a part of the Chinese National Mental Health Survey (CMHS), 2012–15, which reported the prevalence, treatment, and associated disability of depressive disorders in the Chinese general population.  

Methods: The CMHS recruited a representative sample of 28140 Chinese residents (≥ 18 years) by using multistage proportional-to-population-size sampling method. Trained investigators interviewed participants with the Composite International Diagnostic Interview 3.0 to ascertain the presence of lifetime and 12-month depressive disorders according to DSM-IV criteria, including major depressive disorder (MDD), dysthymic disorder (DD), and depressive disorder not otherwise specified (DD-NOS). Participants with 12-month depressive disorders were asked whether they ever received any 12-month treatment for their emotional problems and the specific types of treatment providers. The Quick Inventory of Depressive Symptomatology and Sheehan Disability Scale (SDS) were used to evaluate the severity of and role impairments associated with 12-month depressive symptoms.

Findings: The weighted lifetime and 12-month prevalence rates of any depressive disorder were 6.8% (95%CI: 5.8-7.8%) and 3.6% (95%CI: 3.0-4.2%), respectively; the corresponding figures were 3.4% (95%CI: 2.0-3.9%) and 2.1% (95%CI: 1.8-2.4%) for MDD, 1.4% (95%CI: 1.1-1.7%) and 1.0% (95%CI: 0.8-1.3%) for DD, and 3.2% (95%CI: 2.6-3.9%) and 1.4% (95%CI: 1.1-1.7%) for DD-NOS. Overall, 77.2% of persons with 12-month depressive disorders had role impairment of any SDS domain: 82.2% for MDD, 81.5% for DD, and 64.6% for DD-NOS. Depressed participants reported an average of 41.0 days out of role in the past year due to depression; the corresponding figures were 49.7 days for MDD, 54.9 days for DD, and 12.2 days for DD-NOS. In total, 88.9% of individuals with 12-month depressive disorders had clinically significant depressive symptoms: 93.7% for MDD, 91.7% for DD, and 77.5% for DD-NOS. MDD and DD had similar proportions of “severe” or “very severe” depressive symptoms (43.0% and 42.1%), which were higher than DD-NOS (13.9%). 9.5% of participants with 12-month depressive disorders were treated in any treatment sector: 3.6% in the specialty mental health (SMH), 1.5% in the general medical (GM), 0.3% in the human services (HS), and 3.3% in the complementary-alternative medical (CAM) sector. Respondents with MDD and DYS had the highest proportion of seeking treatment in SMH sector (4.7% and 3.0%) while those with DD-NOS had the highest proportion of seeking treatment in CAM sector (most treatments were Traditional Chinese Medicine) (3.3%). Only 0.5% of participants with depressive disorders were treated adequately. Rates of treatment adequacy of MDD and DYS in SMH sector were 9.2% and 2.4%, respectively. Both rates in GM sector were 0%.

Interpretation: Compared to western countries, our data show a relatively low prevalence of depressive disorders in China. Nevertheless, their associated role impairments, symptom severities, and disabilities are severe.  Importantly, the treatment rates are rather low, let alone adequate treatment. Nationwide programs aiming at removing barriers in availability, accessibility, and acceptability to mental healthcare are needed in China.

Funding: The study was funded by the Special Research Project for Non-profit Public Service of the
Chinese Ministry of Health (grant number 201202022), the National Twelfth Five-Year Plan for
Science and Technology Support of the Chinese Ministry of Science and Technology (grant
numbers 2012BAI01B01 & 2015BAI13B00) and the National Key R&D Program of China (grant
numbers 2017YFC0907800, 2017YFC0907801).

Declaration of Interests: The authors have no conflicts of interest to declare

Ethical Approval: The study protocol of CMHS was approved by the Ethics Committee of the Sixth Hospital of
Peking University (No.: IMH-IRB-2013-13-1).

Suggested Citation

Lu, Jin and Xu, Xiufeng and Huang, Yueqin and Li, Tao and Ma, Chao and Xu, Guangming and Yin, Huifang and Xu, Xiangdong and Ma, Yanjuan and Wang, Limin and Huang, Zhengjing and Yan, Yongping and Wang, Bo and Xiao, Shui-yuan and Zhou, Liang and Li, Lingjiang and Zhang, Yan and Chen, Hongguang and Zhang, Tingting and Yan, Jie and Ding, Hua and Yu, Yaqin and Kou, Changgui and Shen, Zonglin and Jiang, Linlin and Wang, Zhizhong and Sun, Xian and Xu, Yifeng and He, Yanling and Guo, Wan Jun and Jiang, Lijun and Li, Shengyan and Pan, Wen and Wu, Yue and Li, Guohua and Jia, Fujun and Shi, Jianfei and Shen, Zhongxia and Zhang, Ning, The Epidemiology of Depressive Disorders and Service Use in China: Findings from the China Mental Health Survey. Available at SSRN: https://ssrn.com/abstract=3797577 or http://dx.doi.org/10.2139/ssrn.3797577

Jin Lu

Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University

China

Xiufeng Xu

Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University ( email )

China

Yueqin Huang (Contact Author)

Peking University - Institute of Mental Health ( email )

China

Tao Li

Sichuan University - West China Hospital

No 37, Guoxue Road
Wuhou District
Chengdu, Sichuan Province 610041
China

Chao Ma

Peking University - NHC Key Laboratory of Mental Health

Beijing, 100083
China

Guangming Xu

Nankai University - Affiliated Tianjin Anding Hospital ( email )

Tianjin, 300222
China

Huifang Yin

Nankai University - Affiliated Tianjin Anding Hospital

Tianjin, 300222
China

Xiangdong Xu

The Fourth People's Hospital in Urumqi

Urimqi
China

Yanjuan Ma

The Fourth People's Hospital in Urumqi ( email )

Urimqi
China

Limin Wang

Chinese Center for Disease Control and Prevention (China CDC) - National Center for Chronic Non-Communicable Disease Control and Prevention

Beijing
China

Zhengjing Huang

Chinese Center for Disease Control and Prevention (China CDC) - National Center for Chronic Non-Communicable Disease Control and Prevention ( email )

Beijing
China

Yongping Yan

Department of Epidemiology, the Fourth Military Medical University ( email )

No.169, Changlexi Road
Xi'an, Shaanxi 710038
China

Bo Wang

Department of Epidemiology, the Fourth Military Medical University

No.169, Changlexi Road
Xi'an, Shaanxi 710038
China

Shui-yuan Xiao

Central South University - Department of Social Medicine and Health Management ( email )

Changsha
China

Liang Zhou

Guangzhou Medical University - Affiliated Brain Hospital ( email )

Mingxin Road #36
Guangzhou, 510370
United States

Lingjiang Li

Central South University - Second Xiangya Hospital

Changsha, 410083
China

Yan Zhang

Mental Health Institute, the Second Xiangya Hospital, Central South University

Changsha, Hunan 410083
China

Hongguang Chen

Peking University - NHC Key Laboratory of Mental Health

Beijing, 100083
China

Tingting Zhang

Peking University - NHC Key Laboratory of Mental Health

Beijing, 100083
China

Jie Yan

Peking University - Institute of Social Science Survey - ISSS

Beijing
China

Hua Ding

Peking University - Institute of Social Science Survey - ISSS ( email )

Beijing
China

Yaqin Yu

Department of Epidemiology and Biostatistics, School of Public Health, Jilin University ( email )

Guilin Road
Chaoyang, Changchun 130021
China

Changgui Kou

Department of Epidemiology and Biostatistics, School of Public Health, Jilin University ( email )

Guilin Road
Chaoyang, Changchun 130021
China

Zonglin Shen

Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University ( email )

China

Linlin Jiang

Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Division of Prevention and Community Health

Beijing, 102308
China

Zhizhong Wang

Zunyi Medical University ( email )

Zunyi
China

Xian Sun

Department of Epidemiology and Statistics, School of Public Health, Ningxia Medical University

692 Shengli St.
Yinchuan, Ningxia 750004
China

Yifeng Xu

Shanghai Jiao Tong University (SJTU) - Shanghai Clinical Research Center for Mental Health ( email )

Shanghai
China

Yanling He

Shanghai Jiao Tong University (SJTU) - Shanghai Mental Health Center

Shanghai
China

Wan Jun Guo

Zhejiang University - Affiliated Mental Health Center ( email )

Lijun Jiang

Huazhong University of Science and Technology - Department of Hematology

China

Shengyan Li

Third People's Hospital of Qinghai Province ( email )

Wen Pan

Suzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University

No. 1 Shizi Street
Taipei, Jiangsu 215006
Taiwan

Yue Wu

Nanjing Medical University - Wuxi Mental Health Center

Wuxi, Jiangsu Province 214151
China

Guohua Li

Chifeng Anding Hospital

Chifeng
China

Fujun Jia

Guangdong Academy of Medical Sciences - Guangdong Mental Health Center ( email )

Guangdong
China

Jianfei Shi

Department of Psychiatry, Hangzhou Seventh People’s Hospital ( email )

Zhongxia Shen

Third People’s Hospital of Huzhou ( email )

Ning Zhang

Nanjing Medical University - Affiliated Brain Hospital

300 Guangzhou Road
Nanjing, Jiangsu 210029
China