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Association between Ambient PM2·5 and Under- Five, Infant, and Child Mortality in Latin America, 2010- 2015: A Longitudinal Analysis in 337 Cities

13 Pages Posted: 19 Apr 2021

See all articles by Ana Ortigoza

Ana Ortigoza

Drexel University - Urban Health Collaborative

Nelson Gouveia

University of São Paulo (USP)

Josiah Kephart

Drexel University - Urban Health Collaborative

Francisco Javier Prado-Galbarro

UAM Xochimilco - DSc Orphan Drug Laboratory

Guta Friche

Federal University of Minas Gerais (UFMG) - Urban Health Observatory in Belo Horizonte

Brisa N. Sanchez

Drexel University - Urban Health Collaborative

Ana V. Diez-Roux

Drexel University - Urban Health Collaborative

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Abstract

Background. Highly urbanized and rapidly urbanizing countries are facing critical air pollution problems. In Latin American cities, the impact of ambient PM2·5 on child health has not been extensively explored.

Objectives. To examine association between ambient PM2·5 and under-5 mortality (U5MR) infant mortality (IMR) and child mortality (CMR) in Latin American cities.

Methods. We estimated U5MR, IMR, and CMR from 2010 to 2015 for 1,152 sub-city units clustered in 337 cities from Argentina, Brazil, Chile, Colombia, Costa Rica, Guatemala, and Mexico. We retrieved satellite annual PM2·5 for each sub-city unit. Using linear mixed-effects models, we estimated the percent change in U5MR, IMR, and CMR associated with a 1 μg/m3 increase in annual PM2·5, adjusted for city and municipality-level predictors (population growth, GDP, living conditions, service provision, population educational attainment, and mass transit availability).

Results. Over the study period, mean annual PM2·5 was 12·7 μg/m3 (SD 6·3), U5MR and IMR were 14·2 and 12·1 deaths per 1,000 live births, respectively. CMR was 4·8 deaths per 10,000 children. A 1 μg/m3 annual increase in PM2·5 was associated with 0·4% increase in U5MR (95% CI 0.1 to 0.7) and 0·5% increase in IMR (95% CI 0.2 to 0.9) We found no significant association between PM2·5 increases and changes in CMR.

Interpretation. Infants appear to be particularly vulnerable to the deleterious effect of PM2·5. Assuring a clean air environment is important to promote infant survival and health.

Funding: The project is funded by Wellcome Trust Funds, Grant 205177/Z/16/Z.

Declaration of Interest: We declare no competing interests.

Ethical Approval: The SALURBAL study protocol has ethical approval from the Drexel
University IRB with ID # 161 200 5035.

Suggested Citation

Ortigoza, Ana and Gouveia, Nelson and Kephart, Josiah and Prado-Galbarro, Francisco Javier and Friche, Guta and Sanchez, Brisa N. and Diez-Roux, Ana V., Association between Ambient PM2·5 and Under- Five, Infant, and Child Mortality in Latin America, 2010- 2015: A Longitudinal Analysis in 337 Cities. Available at SSRN: https://ssrn.com/abstract=3826204 or http://dx.doi.org/10.2139/ssrn.3826204

Ana Ortigoza (Contact Author)

Drexel University - Urban Health Collaborative ( email )

Philadelphia, PA
United States

Nelson Gouveia

University of São Paulo (USP) ( email )

Av Dr Arnaldo, 455
São Paulo, São Paulo 01246-903
Brazil

Josiah Kephart

Drexel University - Urban Health Collaborative ( email )

Philadelphia, PA
United States

Francisco Javier Prado-Galbarro

UAM Xochimilco - DSc Orphan Drug Laboratory ( email )

Mexico City
Mexico

Guta Friche

Federal University of Minas Gerais (UFMG) - Urban Health Observatory in Belo Horizonte

Av. Antonio Carlos, 6627
Belo Horizonte, Minas Gerais 31270-901
Brazil

Brisa N. Sanchez

Drexel University - Urban Health Collaborative ( email )

Philadelphia, PA
United States

Ana V. Diez-Roux

Drexel University - Urban Health Collaborative ( email )

Philadelphia, PA
United States

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