The Acceptance of COVID-19 Vaccine: A Global Rapid Systematic Review and Meta-Analysis

20 Pages Posted: 8 Jun 2021

See all articles by Sultan Mahmud

Sultan Mahmud

Institute of Statistical Research and Training

Md. Mohsin

Institute of Statistical Research and Training

Sorif Hossain

Institute of Statistical Research and Training; Institute of Statistical Research and Training

Md Mynul Islam

Institute of Statistical Research and Training

Abdul Muyeed

Department of Statistics, Jatiya Kabi Kazi Nazrul Islam University, Trishal, Mymensingh-2220, Bangladesh.

Date Written: May 29, 2021

Abstract

Background: Vaccination seems to be the most effective way to prevent and control the spread of COVID-19, a disease that has been playing havoc with the lives of over 7 billion people across the globe. Vaccine hesitancy is probably the most common problem worldwide. This study aims to inspect the COVID-19 vaccine acceptance rates worldwide among the general population and healthcare workers. In addition, it compares the vaccine acceptance rates between the pre-and post-vaccine approval periods.

Method: A systematic search was conducted on April 25, 2021, through PubMed, MEDLINE, Web of Science, and GOOGLE SCHOLAR databases using PRISMA and MOOSE statements. Q-test, and statistics were used to search for heterogeneity, and Eggers's test and funnel plot were applied to assess the publication bias. The random-effects model was used to estimate the pooled acceptance rates of the COVID-19 vaccines.

Results: The combined COVID-19 vaccine acceptance rate among the general population and healthcare workers (n=1,581,562) was estimated at 61.74%. The vaccine acceptance rate among the general population was 62.66% and the rate among healthcare workers was 57.89%. The acceptance rate decreased from 67.21% to 53.44% among the general population and remained constant among healthcare workers during the pre and post-vaccine approval periods. The acceptance rates also vary in different regions of the world. The highest acceptance rate was found in Western Pacific Region (67.85%) and the lowest was found in African Region (39.51%).

Conclusion: Low COVID-19 vaccine acceptance rate might be a massive barrier to getting rid of the pandemic. More researches are needed to address the responsible factors influencing the global rate of COVID-19 vaccine acceptance. Integrated global efforts are required to remove the barriers.

Note: Funding Statement: The author(s) received no financial support for this research.

Declaration of Interests: There is no conflict of interest among the authors.

Keywords: COVID-19, Global Vaccination, Vaccine Intention, Vaccine Acceptance Rate, Vaccine Hesitancy

Suggested Citation

Mahmud, Sultan and Mohsin, Md. and Hossain, Sorif and Hossain, Sorif and Islam, Md Mynul and Muyeed, Abdul, The Acceptance of COVID-19 Vaccine: A Global Rapid Systematic Review and Meta-Analysis (May 29, 2021). Available at SSRN: https://ssrn.com/abstract=3855987 or http://dx.doi.org/10.2139/ssrn.3855987

Sultan Mahmud (Contact Author)

Institute of Statistical Research and Training ( email )

University of Dhaka
Dhaka 1000
Ramna, Dhaka, Dhaka 1000
Bangladesh

Md. Mohsin

Institute of Statistical Research and Training ( email )

University of Dhaka
Dhaka 1000
Ramna, Dhaka, Dhaka 1000
Bangladesh

Sorif Hossain

Institute of Statistical Research and Training ( email )

University of Dhaka, Bangladesh.
University of Dhaka, Bangladesh.
Dhaka, Dhaka 1000
Bangladesh

Institute of Statistical Research and Training ( email )

University of Dhaka, Bangladesh.
University of Dhaka, Bangladesh.
Dhaka, Dhaka 1000
Bangladesh

Md Mynul Islam

Institute of Statistical Research and Training ( email )

University of Dhaka
Dhaka 1000
Ramna, Dhaka, Dhaka 1000
Bangladesh

Abdul Muyeed

Department of Statistics, Jatiya Kabi Kazi Nazrul Islam University, Trishal, Mymensingh-2220, Bangladesh.

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