Case Histories of Significant Advances: Prozac -- A Controversial, Blockbuster Antidepressant

18 Pages Posted: 16 Jun 2021

See all articles by Amar Bhide

Amar Bhide

Columbia University - Mailman School of Public Health

Srikant Datar

Harvard University - Accounting & Control Unit

Katherine Stebbins

Harvard University - Business School (HBS)

Date Written: June 11, 2021

Abstract

Our case history describes the development of Prozac, a blockbuster drug that transformed the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we chronicle the: 1) prior treatments for depression and the research that provided a foundation for Prozac, before 1970; 2) development of Prozac, from 1971 to 1987; and 3) rapid adoption in the U.S. after 1988.

Keywords: Health Care and Treatment, Technological Innovation, Innovation, Technology Adoption, Invention; Governing Rules, Regulations, and Reforms

Suggested Citation

Bhide, Amar and Datar, Srikant and Stebbins, Katherine, SSRIs and Non-SSRIs (through 1999): Case Histories of Significant Medical Advances (June 11, 2021). Harvard Business School General Management Unit Working Paper No. 20-135, Harvard Business School Accounting & Management Unit Working Paper No. 20-135, Available at SSRN: https://ssrn.com/abstract=3866769 or http://dx.doi.org/10.2139/ssrn.3866769

Amar Bhide (Contact Author)

Columbia University - Mailman School of Public Health ( email )

600 West 168th St., 6th Floor
New York, NY 10032
United States

Srikant Datar

Harvard University - Accounting & Control Unit ( email )

Soldiers Field
Boston, MA 02163
United States
617-495-6543 (Phone)
617-496-7363 (Fax)

Katherine Stebbins

Harvard University - Business School (HBS) ( email )

Soldiers Field Road
Morgan 270C
Boston, MA 02163
United States

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