Polarographic Studies of Ascorbic Acid and Estimation in Pharmaceutical Formulations and Fruit Juices

International Journal of Pharmaceutical Sciences Review and Research 2013

3 Pages Posted: 28 Jul 2021

See all articles by Chetankumar Masram

Chetankumar Masram

S. N. Mor College Tumsar Dist. Bhandara

Ravin M. Jugade

Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur

Date Written: 2013

Abstract

DC polarographic method was developed for estimation of ascorbic acid (vitamin C) in pharmaceutical formulations. Parameters like concentration of supporting electrolyte, maximum suppressor, pH, mercury flow rate and drop time were optimized. Under optimum conditions, a well-defined sigmoid curve was observed with diffusion current proportional to the concentration of ascorbic acid. Analytical quality control was carried out with determination of relative mean deviation, standard deviation and regression studies. The method was found to be simple, rapid and reproducible. The optimized method was applied to various pharmaceutical formulations available in local market. The results obtained were found to be in agreement with the certified values.Keywords:Ascorbic acid, Polarography, Pharmaceutical formulations.

Keywords: Ascorbic acid, Polarography, Pharmaceutical formulations

Suggested Citation

Masram, Chetankumar and Jugade, Ravin M., Polarographic Studies of Ascorbic Acid and Estimation in Pharmaceutical Formulations and Fruit Juices (2013). International Journal of Pharmaceutical Sciences Review and Research 2013, Available at SSRN: https://ssrn.com/abstract=3880324

Chetankumar Masram (Contact Author)

S. N. Mor College Tumsar Dist. Bhandara ( email )

Sant Jagnade Nagar
Tumsar
Tumsar, MA 411212
India
07183233300 (Phone)
07183233301 (Fax)

HOME PAGE: http://www.snmorcollege.org.in

Ravin M. Jugade

Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur ( email )

Department of History, RTM Nagpur University
Amravati Road, Nagpur
Nagpur, MA Maharashtra 440033
India

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