The Role of Behavioral Compliance to Non-Pharmaceutical and Pharmaceutical Interventions in the Fight Against COVID-19: Insights From a Behavior-Disease Economic Epidemic Model Coupled With Optimal Control Theory

27 Pages Posted: 15 Sep 2021

See all articles by Wisdom Avusuglo

Wisdom Avusuglo

Africa-Canada Artificial Intelligence and Data Innovation Consortium (ACADIC), Laboratory for Industrial and Applied Mathematics (LIAM), York University

Nicola Luigi Bragazzi

York University

Ali Asgary

York University

James Orbinski

York University

Jianhong Wu

York University - Laboratory for Industrial and Applied Mathematics; Xi'an Jiaotong University (XJTU) - The Interdisplinary Research Center for Mathematics and Life Sciences

Jude Dzevela Kong

Africa-Canada Artificial Intelligence and Data Innovation Consortium (ACADIC), York University

Date Written: September 11, 2021

Abstract

It is imperative that resources are channeled towards programs that are efficient and cost effective in combating the spread of COVID-19, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2). This study proposed and analyzed control strategies for that purpose. We developed a mathematical disease model within an optimal control framework that allows us to investigate the best approach for curbing COVID-19 epidemic. We address the question, what is the role of community compliance in as a measure for COVID-19 control? Analyzing the impact of community compliance of recommended guidelines by health authorities — examples, social distancing, face mask use, and sanitizing — couple with efforts by health authorities in areas of vaccine provision and effective quarantine — showed that the best intervention in addition to implementation of vaccination programs and effective quarantine measures, is the active incorporation of individuals’ collective behaviors, and that resources should also be directed towards community campaigns on the importance of face mask use, social distancing, and frequent sanitizing, and any other collective activities. We also demonstrated that collective behavioral response of individuals influences the disease dynamics; implying recommended health policy should be contextualized.

Note: Funding: This research is funded by Canada’s International Development Re- search Centre (IDRC) (Grant No. 109559-001).

Declaration of Interests: The authors declare no conflict of interest.

Suggested Citation

Avusuglo, Wisdom and Bragazzi, Nicola Luigi and Asgary, Ali and Orbinski, James and Wu, Jianhong and Wu, Jianhong and Kong, Jude Dzevela, The Role of Behavioral Compliance to Non-Pharmaceutical and Pharmaceutical Interventions in the Fight Against COVID-19: Insights From a Behavior-Disease Economic Epidemic Model Coupled With Optimal Control Theory (September 11, 2021). Available at SSRN: https://ssrn.com/abstract=3922118 or http://dx.doi.org/10.2139/ssrn.3922118

Wisdom Avusuglo

Africa-Canada Artificial Intelligence and Data Innovation Consortium (ACADIC), Laboratory for Industrial and Applied Mathematics (LIAM), York University ( email )

4700 Keele Street
Toronto, Ontario M3J 1P3
Canada

Nicola Luigi Bragazzi (Contact Author)

York University ( email )

4700 Keele Street
Toronto, Ontario M3J 1P3
Canada

Ali Asgary

York University ( email )

4700 Keele Street
Toronto, Ontario M3J 1P3
Canada

James Orbinski

York University

4700 Keele Street
Toronto, Ontario M3J 1P3
Canada

Jianhong Wu

Xi'an Jiaotong University (XJTU) - The Interdisplinary Research Center for Mathematics and Life Sciences ( email )

China

York University - Laboratory for Industrial and Applied Mathematics ( email )

Canada

Jude Dzevela Kong

Africa-Canada Artificial Intelligence and Data Innovation Consortium (ACADIC), York University ( email )

4700 Keele St
Toronto, ON M3J 1P3
Canada

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