Download This Paper
Preprints with The Lancet is part of SSRN´s First Look, a place where journals identify content of interest prior to publication. Authors have opted in at submission to The Lancet family of journals to post their preprints on Preprints with The Lancet. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. Preprints available here are not Lancet publications or necessarily under review with a Lancet journal. These preprints are early stage research papers that have not been peer-reviewed. The findings should not be used for clinical or public health decision making and should not be presented to a lay audience without highlighting that they are preliminary and have not been peer-reviewed. For more information on this collaboration, see the comments published in The Lancet about the trial period, and our decision to make this a permanent offering, or visit The Lancet´s FAQ page, and for any feedback please contact preprints@lancet.com.
An Online Cultural Experience for Mental Health in People Aged 16-24 Compared to a Typical Museum Website: A Randomised Controlled Trial
34 Pages Posted: 27 Oct 2021
More...Abstract
Background: The mental health of young people is a major public health concern that has been exacerbated during the COVID-19 pandemic. There is growing interest in cultural assets such as museums to improve mental health. However, there is a dearth of experimental research regarding the impact of cultural assets on common mental disorders in young adults, and in online experiences, which may improve accessibility.
Methods/design: The O-ACE POP (Online Active Community Engagement Proof of Principle) study is a randomised controlled trial of a co-produced online museum experience named Ways of Being (WoB) compared with the Ashmolean Website (Ash) on negative affect, positive affect and symptoms of anxiety and depression (K10) over a 3-day intervention phase followed by a 6-week follow up assessment.
Findings: 463 people aged 16-24 were randomised: 231 to WoB and 232 to Ash and 349 (74%) completed to 6 weeks. Negative affect was lower over the intervention phase in those allocated to WoB than Ash (WoB-Ash n=448, NA -0.158, p=0·010). For males (179, 39%), those aged 18-24 (422, 91%), non-white ethnic groups (88, 19%), regular users of online culture (238, 51%), those not on antidepressants (363, 78%), and individuals without probable moderate-severe mental health problems (327, 71%) at baseline, negative affect was significantly lower in those allocated to WoB compared to the Ash. Mean K10 reduced over the trial period, from 27·1 (95% CI= 26·6-27·7) to 23·3 (95% CI= 22·5-24·1), as did negative affect whereas positive affect remained relatively stable. Trial recruitment was rapid and feedback positive with broad geographical, occupational and ethnic diversity.
Interpretation: Cultural interventions may improve MH outcomes in a measurable way. Populations that are underserved, both clinically and in research such as non-white ethnic groups, non-students and males and were reached in this study. This demonstrates the importance of measuring psychometric outcomes and the potential for co-produced community cultural resources to support mental health.
Trial Registration: Trial Registration: NCT04663594
Funding: This study is sponsored by the University of Oxford COVID-19 Research Response Fund
and supported by the NIHR Oxford Health Biomedical Research Centre, The Westminster
Foundation and the Huo Family Foundation
Declaration of Interest: AKP and MV were supported by a grant provided by the Huo Family Foundation. All other authors have nothing to declare.
Ethical Approval: The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008. All procedures involving human subjects were approved by the University of Oxford Central University Research Ethics Committee (CUREC), approval reference number R70187/RE007.
Keywords: Depression, Anxiety, Youth, Experimental Medicine
Suggested Citation: Suggested Citation