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Mapping Global Acceptance of COVID-19 Vaccination Updated to June 2021: A Systematic Review and Meta-Analysis
38 Pages Posted: 11 Oct 2021
More...Abstract
Background: The COVID-19 vaccination acceptance is necessary for COVID-19 pandemic control.
Methods: We searched four peer-reviewed databases and three preprint databases for papers published in English from December, 2019 to June, 2021. This review included original survey studies which investigated acceptance, willingness, intention, or uptake of COVID-19 vaccination, and study quality was assessed using the Appraisal tool for Cross-Sectional Studies. We estimated the global acceptance of COVID-19 vaccination, and comparisons across populations, countries, time trends, and subgroups based on sociodemographic characteristics.
Findings: A total of 9547 articles were identified, and 238 articles with 2,484,071 participants were eligible for inclusion in the review. In the 185 studies with high quality, the overall acceptance rate of COVID-19 vaccination was 64.1% (95% CI: 61.9-66.2). Patients with chronic diseases had the highest acceptance rate (69.3%, 58.8-79.8), general residents and healthcare workers had the acceptance rates at 64.4% (61.2-67.6) and 62.8% (58.1-67.5), whereas pregnant/breastfeeding women had the lowest rate (56.5%, 48.6-64.5). The acceptance rate for residents varied across countries, ranging from 19.9% (17.0-22.7) to 92.1% (90.9-93.3). The acceptance rate for residents declined globally between March and October, 2020, and then recovered from November 2020 to March 2021. Females, those aged <60 years old, black individuals, lower educated persons, and lower income persons had lower acceptance of COVID-19 vaccination than their counterparts.
Interpretation: COVID-19 vaccination acceptance varied across different populations and countries, and changed over time. Continuous vaccine acceptance monitoring is necessary to inform public health decision making.
Funding: National Natural Science Foundation of China
Declaration of Interest: The authors declare that they have no competing interests.
Keywords: Key words: COVID-19 vaccine, vaccination, acceptance, willingness, intention, uptake, systematic review
Suggested Citation: Suggested Citation