Investigation of a Limited but Explosive COVID-19 Outbreak in a German Secondary School

29 Pages Posted: 3 Nov 2021 Last revised: 24 Nov 2021

See all articles by Sigrid Baumgarte

Sigrid Baumgarte

Local health authority Hamburg

Felix Hartkopf

Robert Koch Institute

Martin Hölzer

Robert Koch Institute

Max von Kleist

Robert Koch Institute

Sabine Neitz

Gesundheitsamt Nord Hamburg

Martin Kriegel

Technical University Berlin

Kirsten Bollongino

Gesundheitsamt Nord Hamburg

Date Written: October 19, 2021

Abstract

Background
The role of schools as a source of infection and driver in the coronavirus-pandemic has been controversial and is still not completely clarified. To prevent harm and disadvantages for children and adolescents, but also adults, detailed data on school outbreaks is needed, especially when talking about open schools employing evidence-based safety concepts. Here, we investigated the first significant COVID-19 school outbreak in Hamburg, Germany, after the re-opening of schools in 2020.

Methods
Using clinical, laboratory, and contact data and spatial measures for epidemiological and environmental studies combined with whole-genome sequencing (WGS) analysis, we examined the causes and the course of the secondary school outbreak.

Findings
The potential index case was identified by epidemiological tracking and the lessons in classrooms with presumably high virus spreading rates and further infection chains in the setting. Sequence analysis of samples detected one sample of a different virus lineage and 25 virus genomes with almost identical sequences, of which 21 showed 100% similarity. Most infections occurred in connection with two lesson units of the primary case. Likely, 31 students (12-14 years old), two staff members, and three family members were infected in the school or the typical household.

Interpretations
Sequence analysis revealed an outbreak cluster with a single source that was epidemiologically identified as a member of the educational staff. In lesson units, two superspreading events of varying degrees with airborne transmission took place. These were influenced by several parameters including the exposure times, the use of respiratory masks while speaking and spatial or structural conditions at that time.

Note: Funding: None to declare.

Declaration of Interests: The authors declare that they have no conflict of interest.

Ethics Approval Statement: Outbreak investigations of notifiable diseases such as COVID-19 are the legal tasks of the Public Health Service as described under the Public Health Act, and do not require separate medical ethical clearance. Detailed clinical or personal data of single individuals is not shown and seating plans in classrooms were changed after the outbreak. The school and the school authorities agreed to publish the outbreak data.

Keywords: SARS-CoV-2, School outbreak, Superspreading Event, Aerosols, Non-pharmaceutical interventions

Suggested Citation

Baumgarte, Sigrid and Hartkopf, Felix and Hölzer, Martin and von Kleist, Max and Neitz, Sabine and Kriegel, Martin and Bollongino, Kirsten, Investigation of a Limited but Explosive COVID-19 Outbreak in a German Secondary School (October 19, 2021). Available at SSRN: https://ssrn.com/abstract=3946292 or http://dx.doi.org/10.2139/ssrn.3946292

Sigrid Baumgarte (Contact Author)

Local health authority Hamburg ( email )

Eppendorfer Landstraße 59
Hamburg, DE Hamburg 20249
Germany
004933123163091 (Phone)

Felix Hartkopf

Robert Koch Institute ( email )

Berlin
Germany

Martin Hölzer

Robert Koch Institute ( email )

Berlin
Germany
004930187545208 (Phone)

Max Von Kleist

Robert Koch Institute ( email )

Berlin
Germany

Sabine Neitz

Gesundheitsamt Nord Hamburg ( email )

Kümmelstr.7
Hamburg, DE Hamburg 20249
Germany

Martin Kriegel

Technical University Berlin ( email )

Straße des 17
Juni 135
Berlin, 10623
Germany
00493031424170 (Phone)

Kirsten Bollongino

Gesundheitsamt Nord Hamburg ( email )

Kümmelstr.7
Hamburg, DE Hamburg 20249
Germany

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