Nutrition Assessment for Gender-Affirming Hormone Therapy in a Transgender Woman: A Case Study

15 Pages Posted: 11 Jan 2022

See all articles by Dana Chicarelli

Dana Chicarelli

Maryland University of Integrative Health (MUIH)

Rachel Knowles

Maryland University of Integrative Health (MUIH)

Brianne Kellogg

Maryland University of Integrative Health (MUIH)

Date Written: December 1, 2021

Abstract

BACKGROUND The increasing population of transgender patients receiving gender-affirming hormone therapy (GAHT) has raised the question of the need for medical nutrition therapy (MNT) as an adjunctive therapy for supporting health. In transgender patients, GAHT presents both optimal and suboptimal health effects throughout the body, sometimes associated with nutrient deficiencies, supraphysiological hormone levels, and subsequent unpredictable hormone metabolites. Patients may benefit from nutritional assessments when receiving GAHT.

CASE DESCRIPTION A transgender woman in her early 60s presented with supraphysiological levels of estradiol while receiving GAHT. CBCs and metabolic panels had shown suboptimal alkaline phosphatase and creatinine levels, and hormone assessments indicated fluctuating estrogen levels. The patient wished to optimize GAHT and improve her overall well-being. She was tested using two labs that can provide important biochemical pathway information: (1) the Organic Acid Test (OAT - Great Plains) and (2) the Dried Urine Test for Comprehensive Hormones (DUTCH - Precision Analytical).

CONCLUSION This case supported the role of therapeutic intervention paired with nutrition assessment and personalized MNT while implementing GAHT. Common nutritional imbalances in transgender women using GAHT include vitamin D, vitamin B6, and zinc. Additionally, hormone detoxification pathway support may be beneficial to protect transgender patients from pathologies related to supraphysiological estrogen usage.

Note:
Funding Information: No funding was received for the writing of this case report.

Declaration of Interests: There were no conflicts of interest in the making of this case report.

Consent Statement: We received a signed informed consent from the patient who is the subject of this case report.

Keywords: Keywords: Transgender; gender-affirming hormone therapy; nutrition; Organic Acid Test (OAT); Dried Urine Test for Comprehensive Hormones (DUTCH), case report

JEL Classification: I1

Suggested Citation

Chicarelli, Dana and Knowles, Rachel and Kellogg, Brianne, Nutrition Assessment for Gender-Affirming Hormone Therapy in a Transgender Woman: A Case Study (December 1, 2021). Available at SSRN: https://ssrn.com/abstract=3991042 or http://dx.doi.org/10.2139/ssrn.3991042

Dana Chicarelli (Contact Author)

Maryland University of Integrative Health (MUIH) ( email )

United States
4696597743 (Phone)

Rachel Knowles

Maryland University of Integrative Health (MUIH)

United States

Brianne Kellogg

Maryland University of Integrative Health (MUIH)

United States

Do you have a job opening that you would like to promote on SSRN?

Paper statistics

Downloads
197
Abstract Views
853
Rank
290,020
PlumX Metrics