Myocarditis and Sports in the Young: Data from a Nationwide Registry on Myocarditis

24 Pages Posted: 24 Mar 2022

See all articles by Isabelle Schöffl

Isabelle Schöffl

Universitätsklinikum Erlangen

Sophia Holler

affiliation not provided to SSRN

Sven Dittrich

affiliation not provided to SSRN

Thomas Pickardt

affiliation not provided to SSRN

Bernd Opgen-Rhein

affiliation not provided to SSRN

Martin Boehne

affiliation not provided to SSRN

Bardo Wannenmacher

affiliation not provided to SSRN

Katja Reineker

University of Freiburg - Department for Paediatric Cardiology

Gesa Wiegand

University of Tuebingen - Department for Paediatric Cardiology

Tobias Hecht

Ruhr University of Bochum - Center for Congenital Heart Disease/Pediatric Cardiology

Michael Kaestner

University Hospital Ulm - Pediatric Cardiology

Daniel Messroghli

DZHK - German Centre for Cardiovascular Research

Stephan Schubert

German Heart Center Berlin - Department of Congenital Heart Disease and Pediatric Cardiology

Franziska Seidel

German Heart Center Berlin - Department of Congenital Heart Disease and Pediatric Cardiology

Annika Weigelt

affiliation not provided to SSRN

Abstract

Background: Myocarditis represents one of the most common causes of Sudden Cardiac Death (SCD) in children. Myocardial involvement during a viral infection is associated with intensive exertion. Recommendations for return to sports are based on cohort and case studies only. This study aims to investigate the relationship between physical activity and myocarditis in the young.

Patient: Every patient in the MYKKE registry fulfilling criteria for suspicion of myocarditis was sent a questionnaire regarding the physical activity before, during and after the onset of myocarditis.

Method: This study is a subproject within the MYKKE registry, a multicenter registry for children and adolescents with suspected myocarditis. The observation period for this analysis was 93 months (September 2013 - June 2021). Anamnestic, cardiac MRI, echocardiography, biopsy and laboratory records from every patient were retrieved from the MYKKE registry database.

Results: 58 patients (mean age 14.6 years) were enrolled from 10 centers. Most patients participated in curricular physical activity and 36% in competitive sports before the onset of myocarditis. There was no significant difference of heart function at admission between the physically active and inactive subjects (EF of 51.8 ± 8.6 % for the active group vs. 54.4 ± 7.7%). The recommendations regarding the return to sports varied widely and followed current guidelines in 45%. Most patients did not receive an exercise test before returning to sports.

Discussion: Sports before the onset of myocarditis was not associated with severe outcome. There is still a discrepancy between current literature and actual recommendations given by health care providers.

Note:
Funding Information: This work was supported by the German Heart Foundation (September 2013 to June 2021).

Declaration of Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Ethics Approval Statement: The study was approved by the ethical committee of the Charité Universitätsmedizin Berlin, Germany and the Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.

Keywords: return to sports, Sudden cardiac death, physical activity, infectious heart disease

Suggested Citation

Schöffl, Isabelle and Holler, Sophia and Dittrich, Sven and Pickardt, Thomas and Opgen-Rhein, Bernd and Boehne, Martin and Wannenmacher, Bardo and Reineker, Katja and Wiegand, Gesa and Hecht, Tobias and Kaestner, Michael and Messroghli, Daniel and Schubert, Stephan and Seidel, Franziska and Weigelt, Annika, Myocarditis and Sports in the Young: Data from a Nationwide Registry on Myocarditis. Available at SSRN: https://ssrn.com/abstract=4065640 or http://dx.doi.org/10.2139/ssrn.4065640

Isabelle Schöffl (Contact Author)

Universitätsklinikum Erlangen ( email )

Erlangen
Germany

Sophia Holler

affiliation not provided to SSRN ( email )

No Address Available

Sven Dittrich

affiliation not provided to SSRN ( email )

No Address Available

Thomas Pickardt

affiliation not provided to SSRN ( email )

No Address Available

Bernd Opgen-Rhein

affiliation not provided to SSRN ( email )

No Address Available

Martin Boehne

affiliation not provided to SSRN ( email )

No Address Available

Bardo Wannenmacher

affiliation not provided to SSRN ( email )

No Address Available

Katja Reineker

University of Freiburg - Department for Paediatric Cardiology ( email )

Freiburg
Germany

Gesa Wiegand

University of Tuebingen - Department for Paediatric Cardiology ( email )

Tübingen
Germany

Tobias Hecht

Ruhr University of Bochum - Center for Congenital Heart Disease/Pediatric Cardiology ( email )

Bad Oeynhausen
Germany

Michael Kaestner

University Hospital Ulm - Pediatric Cardiology ( email )

Ulm
Germany

Daniel Messroghli

DZHK - German Centre for Cardiovascular Research ( email )

Oudenarder Straße 16
Building D/04 (1st Floor)
Berlin, 13316
Germany

Stephan Schubert

German Heart Center Berlin - Department of Congenital Heart Disease and Pediatric Cardiology ( email )

Germany

Franziska Seidel

German Heart Center Berlin - Department of Congenital Heart Disease and Pediatric Cardiology ( email )

Germany

Annika Weigelt

affiliation not provided to SSRN ( email )

No Address Available

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