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Most Accurate Prevalence of PTSD and Common Mental Disorders in Healthcare Workers in England: A Two-Phase Epidemiological Survey

18 Pages Posted: 2 Jun 2022

See all articles by Hannah R. Scott

Hannah R. Scott

King’s College London - Department of Psychological Medicine

Sharon A. M. Stevelink

King’s College London - King’s Centre for Military Health Research

Rafael Gafoor

University College London - Division of Psychiatry

Danielle Lamb

University College London - Division of Psychiatry

Ioannis Bakolis

King’s College London - Department of Biostatistics & Health Informatics

Rupa Bhundia

King’s College London - Department of Psychological Medicine

Ewan Carr

King’s College London - Department of Biostatistics & Health Informatics

Mary Jane Docherty

Government of the United Kingdom - South London and Maudsley NHS Foundation Trust

Sam Gnanapragasam

King’s College London - Department of Psychological Medicine

Siobhan Hegarty

King’s College London - Department of Psychological Medicine

Matthew Hotopf

King’s College London - Department of Psychological Medicine

Ira Madan

Guy's and St Thomas' NHS Foundation Trust - Department of Occupational Health

Sally McManus

City University London - Violence and Society Centre

Paul Moran

University of Bristol - Centre for Academic Mental Health

Emilia Souliou

King’s College London - Department of Psychological Medicine

Rosalind Raine

University College London - Division of Psychiatry

Reza Razavi

King’s College London - School of Biomedical Engineering & Imaging Sciences

Danny Weston

King’s College London - Department of Psychological Medicine

Neil Greenberg

King’s College London - Department of Psychological Medicine

Simon Wessely

King’s College London - Department of Psychological Medicine

More...

Abstract

Background: Previous studies on the impact of the COVID-19 pandemic on healthcare workers’ (HCWs) mental health have relied on self-reported screening measures to estimate point prevalence. Screening measures, which are designed to be sensitive, have low positive predictive value and often overestimate prevalence. We now present a more accurate prevalence of common mental disorders (CMDs) and post-traumatic stress disorder (PTSD) among HCWs in England using diagnostic interviews.

Methods: A two-stage, cross-sectional study comprising diagnostic interviews (n=337) within a larger multi-site longitudinal cohort of HCWs (n=23,462) conducted during the COVID-19 pandemic. This study included two representative participant groups: i) 243 participants were screened with the General Health Questionnaire (GHQ-12) and assessed with the Clinical Interview Schedule – Revised (CIS-R) for CMDs; ii) 94 participants were screened with the PCL-6 and assessed with the Clinician Administered PTSD Scale (CAPS-5) for DSM-5 for PTSD.

Findings: The GHQ screening caseness for any CMD was 52.8% (95% CI 51.7 to 53.8). Using CIS-R diagnostic interviews, the estimated population prevalence of generalised anxiety disorder was 14.3% (95% CI 10.4 to 19.2) and for depression 13.7% (95% CI 10.1 to 18.3). The PCL-6 screening caseness for PTSD was 25.4% (95% CI 24.3 to 26.5). Using CAPS-5 diagnostic interviews, the estimated population prevalence of PTSD was 7.9% (95% CI 4.0 to 15.1).

Conclusion: The prevalence estimates of CMD and PTSD in HCWs are considerably lower when assessed through diagnostic interviews than when estimated using screening tools. Nevertheless, 1-in-5 HCWs met the threshold for a diagnosable mental disorder which might benefit from clinical intervention.

Funding Information: This study was supported by the Medical Research Council (MR/V034405/1); UCL/Wellcome (ISSF3/ H17RCO/C3); Rosetrees (M952); NHS England and Improvement; Economic and Social Research Council (ES/V009931/1); National Institute of Health and Care Research (NIHR) Biomedical Research Centre at the Maudsley and King's College London (KCL); NIHR Protection Research Unit in Emergency Preparedness and Response at KCL.

Declaration of Interests: MH and SW are senior NIHR Investigators. NG sits on the NHSEI expert reference group and also runs March on Stress which is a psychological health consultancy that provides mental health training to some NHS Trusts. All other authors declare no competing interests.

Ethics Approval Statement: Ethical approval for the study was granted by the Health Research Authority (reference: 20/HRA/2107, IRAS: 282686) and local Trust Research and Development approval. The study was approved as having Urgent Public Health Status by the NIHR in August 2020.

Keywords: common mental disorders, epidemiology, healthcare workers, mental health, prevalence, post-traumatic stress disorder

Suggested Citation

Scott, Hannah R. and Stevelink, Sharon A. M. and Gafoor, Rafael and Lamb, Danielle and Bakolis, Ioannis and Bhundia, Rupa and Carr, Ewan and Docherty, Mary Jane and Gnanapragasam, Sam and Hegarty, Siobhan and Hotopf, Matthew and Madan, Ira and McManus, Sally and Moran, Paul and Souliou, Emilia and Raine, Rosalind and Razavi, Reza and Weston, Danny and Greenberg, Neil and Wessely, Simon, Most Accurate Prevalence of PTSD and Common Mental Disorders in Healthcare Workers in England: A Two-Phase Epidemiological Survey. Available at SSRN: https://ssrn.com/abstract=4113120 or http://dx.doi.org/10.2139/ssrn.4113120

Hannah R. Scott

King’s College London - Department of Psychological Medicine ( email )

Sharon A. M. Stevelink (Contact Author)

King’s College London - King’s Centre for Military Health Research ( email )

Rafael Gafoor

University College London - Division of Psychiatry ( email )

Danielle Lamb

University College London - Division of Psychiatry ( email )

Gower Street
London, WC1E 6BT
United Kingdom

Ioannis Bakolis

King’s College London - Department of Biostatistics & Health Informatics ( email )

Rupa Bhundia

King’s College London - Department of Psychological Medicine ( email )

Ewan Carr

King’s College London - Department of Biostatistics & Health Informatics ( email )

Mary Jane Docherty

Government of the United Kingdom - South London and Maudsley NHS Foundation Trust ( email )

Monks Orchard Road
Beckenham, BR3 3BX
United Kingdom

Sam Gnanapragasam

King’s College London - Department of Psychological Medicine ( email )

Siobhan Hegarty

King’s College London - Department of Psychological Medicine ( email )

Matthew Hotopf

King’s College London - Department of Psychological Medicine ( email )

Ira Madan

Guy's and St Thomas' NHS Foundation Trust - Department of Occupational Health ( email )

United Kingdom

Sally McManus

City University London - Violence and Society Centre ( email )

London
United Kingdom

Paul Moran

University of Bristol - Centre for Academic Mental Health ( email )

Emilia Souliou

King’s College London - Department of Psychological Medicine ( email )

Rosalind Raine

University College London - Division of Psychiatry ( email )

Reza Razavi

King’s College London - School of Biomedical Engineering & Imaging Sciences ( email )

Strand
London, WC2R 2LS
United Kingdom

Danny Weston

King’s College London - Department of Psychological Medicine ( email )

Neil Greenberg

King’s College London - Department of Psychological Medicine ( email )

Simon Wessely

King’s College London - Department of Psychological Medicine ( email )

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