
Preprints with The Lancet is part of SSRN´s First Look, a place where journals identify content of interest prior to publication. Authors have opted in at submission to The Lancet family of journals to post their preprints on Preprints with The Lancet. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. Preprints available here are not Lancet publications or necessarily under review with a Lancet journal. These preprints are early stage research papers that have not been peer-reviewed. The findings should not be used for clinical or public health decision making and should not be presented to a lay audience without highlighting that they are preliminary and have not been peer-reviewed. For more information on this collaboration, see the comments published in The Lancet about the trial period, and our decision to make this a permanent offering, or visit The Lancet´s FAQ page, and for any feedback please contact preprints@lancet.com.
Most Accurate Prevalence of PTSD and Common Mental Disorders in Healthcare Workers in England: A Two-Phase Epidemiological Survey
18 Pages Posted: 2 Jun 2022
More...Abstract
Background: Previous studies on the impact of the COVID-19 pandemic on healthcare workers’ (HCWs) mental health have relied on self-reported screening measures to estimate point prevalence. Screening measures, which are designed to be sensitive, have low positive predictive value and often overestimate prevalence. We now present a more accurate prevalence of common mental disorders (CMDs) and post-traumatic stress disorder (PTSD) among HCWs in England using diagnostic interviews.
Methods: A two-stage, cross-sectional study comprising diagnostic interviews (n=337) within a larger multi-site longitudinal cohort of HCWs (n=23,462) conducted during the COVID-19 pandemic. This study included two representative participant groups: i) 243 participants were screened with the General Health Questionnaire (GHQ-12) and assessed with the Clinical Interview Schedule – Revised (CIS-R) for CMDs; ii) 94 participants were screened with the PCL-6 and assessed with the Clinician Administered PTSD Scale (CAPS-5) for DSM-5 for PTSD.
Findings: The GHQ screening caseness for any CMD was 52.8% (95% CI 51.7 to 53.8). Using CIS-R diagnostic interviews, the estimated population prevalence of generalised anxiety disorder was 14.3% (95% CI 10.4 to 19.2) and for depression 13.7% (95% CI 10.1 to 18.3). The PCL-6 screening caseness for PTSD was 25.4% (95% CI 24.3 to 26.5). Using CAPS-5 diagnostic interviews, the estimated population prevalence of PTSD was 7.9% (95% CI 4.0 to 15.1).
Conclusion: The prevalence estimates of CMD and PTSD in HCWs are considerably lower when assessed through diagnostic interviews than when estimated using screening tools. Nevertheless, 1-in-5 HCWs met the threshold for a diagnosable mental disorder which might benefit from clinical intervention.
Funding Information: This study was supported by the Medical Research Council (MR/V034405/1); UCL/Wellcome (ISSF3/ H17RCO/C3); Rosetrees (M952); NHS England and Improvement; Economic and Social Research Council (ES/V009931/1); National Institute of Health and Care Research (NIHR) Biomedical Research Centre at the Maudsley and King's College London (KCL); NIHR Protection Research Unit in Emergency Preparedness and Response at KCL.
Declaration of Interests: MH and SW are senior NIHR Investigators. NG sits on the NHSEI expert reference group and also runs March on Stress which is a psychological health consultancy that provides mental health training to some NHS Trusts. All other authors declare no competing interests.
Ethics Approval Statement: Ethical approval for the study was granted by the Health Research Authority (reference: 20/HRA/2107, IRAS: 282686) and local Trust Research and Development approval. The study was approved as having Urgent Public Health Status by the NIHR in August 2020.
Keywords: common mental disorders, epidemiology, healthcare workers, mental health, prevalence, post-traumatic stress disorder
Suggested Citation: Suggested Citation