Associations between Dietary Profiles and Perfluoroalkyl Acids in Inuit Youth and Adults

24 Pages Posted: 21 Jul 2022

See all articles by Amira Aker

Amira Aker

affiliation not provided to SSRN

Pierre Ayotte

Université Laval

Élyse Caron-Beaudoin

affiliation not provided to SSRN

Amila De Silva

Environment and Climate Change Canada

Sylvie Ricard

affiliation not provided to SSRN

Mélanie Lemire

affiliation not provided to SSRN

Abstract

BackgroundPerfluoroalkyl acids (PFAAs), a subset of perfluoroalkyl substances (PFAS), are synthetic chemicals used in various industrial and consumer applications. They are exceptionally stable and highly mobile in the environment, and have been detected in high concentrations in Arctic wildlife and Nunavik Inuit. The study’s objective was to study the association between dietary profiles in Nunavik and plasma PFAAs concentrations.MethodsThe study used data from the Qanuilirpitaa? 2017 Nunavik Inuit Health Survey (Q2017). Nine PFAAs congeners were measured in plasma samples. Dietary profiles were identified using latent profile analysis. Two sets of dietary profiles were included; the first included market (store-bought) and country foods (harvested or hunted from the land), and the second included only country foods. Multiple linear regression models regressed log-transformed PFAAs concentrations against the dietary profiles, adjusting for sociodemographic variables.ResultsWe identified strong associations between the dietary profile defined by frequent country food consumption and all PFAAs congeners (PFOA, PFNA, PFDA, PFUnDA, PFHxS, and PFOS) compared to the dietary profile defined by frequent market food consumption. Individuals with low rates of consumption had higher concentrations of all PFAAs congeners compared to individuals with frequent market food consumption. The associations were stronger with profiles defined by more frequent country food consumption, and particularly those with increased marine mammal consumption. PFDA, PFUnDA, and PFOS were particularly associated with high country food consumption frequency, such that their concentrations increased by approximately 67-83% compared to those reporting no or very little consumption of any country foods.ConclusionsIncreased country food consumption was strongly associated with higher PFAAs concentrations, particularly PFOS and long-chain PFAAs congeners. The results provide further evidence that the quality of country foods is being threatened by PFAAs contamination. Additional national and international regulations are required to protect the Arctic and its inhabitants from these pollutants.

Keywords: PFAS, dietary exposures, exposure determinants, Indigenous, Inuit

Suggested Citation

Aker, Amira and Ayotte, Pierre and Caron-Beaudoin, Élyse and De Silva, Amila and Ricard, Sylvie and Lemire, Mélanie, Associations between Dietary Profiles and Perfluoroalkyl Acids in Inuit Youth and Adults. Available at SSRN: https://ssrn.com/abstract=4168679 or http://dx.doi.org/10.2139/ssrn.4168679

Amira Aker (Contact Author)

affiliation not provided to SSRN ( email )

No Address Available

Pierre Ayotte

Université Laval ( email )

2214 Pavillon J-A. DeSeve
Quebec, G1K 7P4
Canada

Élyse Caron-Beaudoin

affiliation not provided to SSRN ( email )

No Address Available

Amila De Silva

Environment and Climate Change Canada ( email )

Gatineau
Canada

Sylvie Ricard

affiliation not provided to SSRN ( email )

No Address Available

Mélanie Lemire

affiliation not provided to SSRN ( email )

No Address Available

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