Association between Oral Health and Airflow Limitation: Analysis Using a Nationwide Database

32 Pages Posted: 12 Sep 2022

See all articles by Sun-Hyung Kim

Sun-Hyung Kim

Chungbuk National University - College of Medicine

Seonhye Ku

Korea University

Jung-Ae Kim

Chungbuk National University - Chungbuk National University Hospital

YoHan Im

Chungbuk National University - Chungbuk National University Hospital

Jun Yeun Cho

Chungbuk National University - College of Medicine

Hyeran Kang

Chungbuk National University - College of Medicine

Yoon Mi Shin

Chungbuk National University - College of Medicine

Eung-Gook Kim

Chungbuk National University - Department of Chemistry

Ki Man Lee

Chungbuk National University - College of Medicine

Kang Hyeon Choe

Chungbuk National University - College of Medicine

Hyun Lee

Hanyang University - Division of Pulmonary Medicine and Allergy

Bumhee Yang

Chungbuk National University - Chungbuk National University Hospital; Chungbuk National University - College of Medicine

Abstract

Background: Although poor oral health is a common comorbidity in individuals with chronic obstructive pulmonary disease (COPD), few studies have comprehensively evaluated this association. Furthermore, the association between oral health and the severity of COPD has not been well elucidated.

Methods: Using a population-based nationwide survey, we classified individuals according to the presence or absence of airflow limitation (AFL). We evaluated the association between AFL severity and the number of remaining teeth; the presence of periodontitis; Decayed, Missing, and Filled Teeth (DMFT) index; and denture wearing.

Results: Compared with the control group, the AFL group had a higher proportion of periodontitis (88.8% vs 79.4%), complete denture (6.2% vs 1.6%), and high DMFT index (37.3% vs 27.8%) (P <0.001 for all). In multivariable analyses, denture status (removable partial denture [adjusted odds ratio (aOR) = 1.12, 95% confidence interval (95%CI) = 1.04–1.20] and complete denture [aOR = 1.52, 95%CI = 1.10–2.05]), high DMFT index (aOR = 1.13, 95%CI = 1.02–1.24), and fewer permanent teeth (0–19) (aOR = 1.32, 95%CI = 1.12–1.52) were significantly associated with AFL. Furthermore, those with severe to very severe AFL had a significantly higher proportion of complete denture (aOR = 2.41, 95%CI = 1.11–3.71) and fewer remaining teeth (0–19) (aOR = 2.29, 95%CI = 1.57–3.01).

Conclusions: Denture wearing, high DMFT index, and fewer permanent teeth are significantly associated with AFL. Furthermore, high DMFT index and fewer permanent teeth are significantly associated with the severity of AFL.

Note:

Funding Information: This work was supported by grants from the National Research Foundation (NRF) of Korea (2020R1A5A2017476). This work was also supported by Chungbuk National University Hospital 2021.

Declaration of Interests: None.

Ethics Approval Statement: The study protocol was approved by the Institutional Review Board of Chungbuk National University Hospital (application no. 2022-02-017). The Korea NHANES surveys were approved by the relevant institutional review boards; and written, informed consent was provided by all participants.

Keywords: oral health, chronic obstructive pulmonary disease, airflow limitation, DMFT index, denture, periodontitis

Suggested Citation

Kim, Sun-Hyung and Ku, Seonhye and Kim, Jung-Ae and Im, YoHan and Cho, Jun Yeun and Kang, Hyeran and Shin, Yoon Mi and Kim, Eung-Gook and Lee, Ki Man and Choe, Kang Hyeon and Lee, Hyun and Yang, Bumhee, Association between Oral Health and Airflow Limitation: Analysis Using a Nationwide Database. Available at SSRN: https://ssrn.com/abstract=4201218 or http://dx.doi.org/10.2139/ssrn.4201218

Sun-Hyung Kim

Chungbuk National University - College of Medicine ( email )

Seonhye Ku

Korea University ( email )

1 Anam-dong 5 ka
Seoul, 136-701
Korea, Republic of (South Korea)

Jung-Ae Kim

Chungbuk National University - Chungbuk National University Hospital ( email )

Korea, Republic of (South Korea)

YoHan Im

Chungbuk National University - Chungbuk National University Hospital ( email )

Korea, Republic of (South Korea)

Jun Yeun Cho

Chungbuk National University - College of Medicine ( email )

Hyeran Kang

Chungbuk National University - College of Medicine ( email )

Yoon Mi Shin

Chungbuk National University - College of Medicine ( email )

Eung-Gook Kim

Chungbuk National University - Department of Chemistry ( email )

Ki Man Lee

Chungbuk National University - College of Medicine ( email )

Kang Hyeon Choe

Chungbuk National University - College of Medicine ( email )

Hyun Lee

Hanyang University - Division of Pulmonary Medicine and Allergy ( email )

Bumhee Yang (Contact Author)

Chungbuk National University - Chungbuk National University Hospital ( email )

Korea, Republic of (South Korea)

Chungbuk National University - College of Medicine ( email )

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