Facile Preparation of Electroactive Au@Ru Cups for Sensitive Bisphenol a Detection

Abstract

Bisphenol A (BPA) was illegally added in the food packaging and infiltrated into food, which possessed potential hazards to human health. The fabrication of strong and stable electroactive beacons was of vital to develop sensitive and accurate electrochemical aptasensor for BPA detection. Herein, a facile method was proposed for the control growth of Ru dots on the surface of Au cups at ordinary pressure, inducing the formation of burr-like Au@Ru cups. Au@Ru cups exhibited strong electro-oxidization signal at 1.0 V, owing to the electron transfer process between Ru0 and Rux+. The large specific surface area of cup structures enabled the deposition of much more electroactive Ru sites for the formation of burr-like Au@Ru cups. The electro-oxidization signal was enhanced and the peak intensity reached up to 143 μA. Au@Ru cups served as the alternative electrochemical beacons for the sensitive detection of BPA in the range of 1 nM to 200 μM. The limit of detection (LOD) was 0.5 nM. This work provided a new principle for the design of strong electroactive Ru-based nanocomposites for the detection applications.

Keywords: Electroactive, Au@Ru cups, Electro-oxidization, Bisphenol A, Detection