Micro Gas Chromatography Column Coated With Ionic Liquid/Metal-Organic Framework Composites as the Stationary Phase

Abstract

Micro gas chromatography (μGC) is a new technique for rapid, efficient, and on-site analysis of complex gas mixtures. However, the repeatability and resolution of the μGC are low due to the shorter column length. Developing a new stationary phase to address these deficiencies is desirable to improve μGC field separation performance. In this paper, the μGC-IL/MOF and the μGC-IL were prepared using [P66614][NTf2]/ZIF-8 and [P66614][NTf2] as the stationary phase, respectively. [P66614][NTf2]/ZIF-8 composite stationary phase material has high specific surface area and porous structure, which increases the diffusion of gas molecules in the column. Compared to μGC-IL, μGC-IL/MOF can separate n-alkanes mixture(C5-C12) with higher resolution, and the resolution (R) of C5-C6 was increased by 211.00% in particular. The μGC-IL/MOF can separate C5-C12 in about 5 min with optimal carrier gas velocity and column temperature, and the resolution of adjacent peaks was 1.555 minimum, which meets the requirements of quantitative analysis (R>1.5). Therefore, the μGC-IL/MOF is expected to be integrated into portable devices for environmental monitoring and medical diagnosis in the future.

Keywords: Micro gas chromatography MEMS, IL/MOF, High resolution.