header

Possible Anxiolytic Effects of Cannabidiol (Cbd) Administration on Feline Response to a Fear Response Test

13 Pages Posted: 28 Jun 2023 Publication Status: Preprint

Abstract

The purpose of the study was to investigate the effects of cannabidiol (CBD) administration in reducing sound-induced fear in healthy domestic cats in a laboratory model of thunderstorm simulation. Forty cats naïve to the current testing were randomly divided into two administration groups (CBD and placebo).  Each group was then exposed to thunderstorm test twice; once at the beginning of the administration (the administration of CBD at 4.0 mg/kg/day over a 2-week-period, or the administration of the same amount of sunflower oil as placebo) and once after the end of the administration. Subsequently, the cats were video-assessed by two trained observers, independently from one another, on a 7-point scale for stress levels, using Cat-Stress-Score (CSS). CBD significantly reduced the CSS in the CBD group after the administration as compared with before the administration while no significant change was recorded in the placebo group. The results indicate that CBD could be a useful option to treat noise-induced fear that is a significant concern for a number of cat owners.

Keywords: anxiety, cat, cannabidiol, CBD, fear

Suggested Citation

Masataka, Nobuo, Possible Anxiolytic Effects of Cannabidiol (Cbd) Administration on Feline Response to a Fear Response Test. Available at SSRN: https://ssrn.com/abstract=4480358 or http://dx.doi.org/10.2139/ssrn.4480358

Nobuo Masataka (Contact Author)

Kyoto University ( email )

Yoshida-Honmachi
Sakyo-ku
Kyoto, 606-8501
Japan

Do you have negative results from your research you’d like to share?

Paper statistics

Downloads
75
Abstract Views
1,180
PlumX Metrics