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Reducing the Carbon Footprint of General Anaesthesia: A Comparison of Total Intravenous Anaesthesia vs. Mixed Anaesthetic Strategy in 47,157 Adult Patients

17 Pages Posted: 1 Nov 2023

See all articles by Matthieu Bernat

Matthieu Bernat

Aix-Marseille University

Arthur Boyer

Aix-Marseille University

Manon Roche

Aix-Marseille University - Assistance Publique - Hôpitaux de Marseille (AP-HM)

Corentin Richard

Aix-Marseille University

Lionel Bouvet

University of Claude Bernard Lyon 1 - Hospices Civils de Lyon

Anne Remacle

Aix-Marseille University

Guillaume Fond

Aix Marseille Université - CEReSS-Centre d'Etude et de Recherche sur les Services de Santé et la Qualité de vie

Nicolas Bruder

Aix-Marseille University - Department of Anesthesia and Intensive Care Unit

Marc Leone

Aix-Marseille University - Department of Anesthesia and Intensive Care Unit

Laurent Zieleskiewicz

Aix-Marseille University - Department of Anesthesia and Intensive Care Unit

SIAGM (Sustainability In Anaesthesia Group of Marseille ) Group

Independent

More...

Abstract

Background: Global warming is a public health concern. Volatile anaesthetics significantly increase healthcare's carbon footprint. Laboratory studies suggest that total intravenous anaesthesia (TIVA) is less carbon intensive than volatile anaesthesia to perform general anaesthesia in adults, with equal quality of care. We aimed to compare the carbon footprint per general anaesthesia of an exclusive TIVA strategy vs. a mixed TIVA-volatile strategy, and to extrapolate these results at a global level.

Methods: This comparative retrospective study was conducted over two years in two French hospitals, one using TIVA only and one using a mixed strategy including both TIVA and inhaled anaesthesia techniques. Based on pharmacy procurement records, quantity of anaesthetic sedative drugs was converted to CO2-equivalent (CO2e). Primary outcome was the difference in carbon footprint per intervention between the two strategies and its projection at a global scale.

Findings: From January 1, 2021, to December 31, 2022, 24,962 patients were operated under general anaesthesia in the TIVA strategy and 22,017 in the mixed strategy. Carbon footprint of sedation per intervention in TIVA strategy was 20 times lower than the mixed strategy, with emissions of 2.32 kg and 47.97 kg CO2e per intervention, respectively. Global extrapolation yielded 468 kilotons and 9,596 kilotons of CO2e annually for TIVA and mixed strategies, respectively.

Interpretation: TIVA strategy significantly reduces carbon footprint of sedation in general anaesthesia in adult patients compared to a mixed strategy. Transitioning globally to TIVA could considerably decrease carbon footprint of general anaesthesia but could increase plastic and water pollution. Further research is warranted to assess the risk-benefit ratio of widespread TIVA adoption.

Funding: None

Declaration of Interest: We declare no competing interests.

Ethical Approval: According to the French law, our study has been classified as research not involving human subjects, and was approved by our local ethic committee (GDPR 2019-01 PADS23-195).

Keywords: anaesthesia, climate change, global warming, carbon footprint, environment, sustainability, TIVA, halogenated

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Suggested Citation

Bernat, Matthieu and Boyer, Arthur and Roche, Manon and Richard, Corentin and Bouvet, Lionel and Remacle, Anne and Fond, Guillaume and Bruder, Nicolas and Leone, Marc and Zieleskiewicz, Laurent and Group, SIAGM (Sustainability In Anaesthesia Group of Marseille ), Reducing the Carbon Footprint of General Anaesthesia: A Comparison of Total Intravenous Anaesthesia vs. Mixed Anaesthetic Strategy in 47,157 Adult Patients. Available at SSRN: https://ssrn.com/abstract=4617151 or http://dx.doi.org/10.2139/ssrn.4617151

Matthieu Bernat (Contact Author)

Aix-Marseille University ( email )

Arthur Boyer

Aix-Marseille University ( email )

Manon Roche

Aix-Marseille University - Assistance Publique - Hôpitaux de Marseille (AP-HM) ( email )

Corentin Richard

Aix-Marseille University ( email )

Lionel Bouvet

University of Claude Bernard Lyon 1 - Hospices Civils de Lyon ( email )

Anne Remacle

Aix-Marseille University ( email )

Guillaume Fond

Aix Marseille Université - CEReSS-Centre d'Etude et de Recherche sur les Services de Santé et la Qualité de vie ( email )

Nicolas Bruder

Aix-Marseille University - Department of Anesthesia and Intensive Care Unit ( email )

Marc Leone

Aix-Marseille University - Department of Anesthesia and Intensive Care Unit ( email )

Marseille
France

Laurent Zieleskiewicz

Aix-Marseille University - Department of Anesthesia and Intensive Care Unit ( email )

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