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A Decade of a Regional Network for St-Segment Elevation Myocardial Infarction Care in Brazil: Assessment of Improvements in Reperfusion Rates and Quality of Care

20 Pages Posted: 18 Dec 2023

See all articles by Pollianna de Souza Roriz

Pollianna de Souza Roriz

UNIFACS- Universidade Salvador

Isabella B. B. Ferreira

Bahiana School of Medicine and Public Health

Fabiana Benevides Pontes

Hospital Ana Nery

Antônio Fernando Machado

UNIFACS- Universidade Salvador

Tércio Aguiar

UNIFACS- Universidade Salvador

Marcos Antônio Almeida Matos

Bahiana School of Medicine and Public Health

Ivan Paiva

Universidade Salvador (UNIFACS)

Rodrigo C. Menezes

Instituto de Pesquisa Clínica e Translacional

Bruno B. Andrade

Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative; Oswaldo Cruz Foundation (FIOCRUZ) - Laboratório de Inflamação e Biomarcadores

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Abstract

Background: Continuous investment and systematic evaluation of program accomplishments are required to achieve excellence in ST-segment elevation myocardial infarction (STEMI) care, especially in resource-limited settings. Therefore, this study evaluates the impact of problem-driven interventions on reperfusion use rate in a long-term operating STEMI network from a low- to middle-income country.

Methods: This is a healthcare improvement evaluation study of Salvador’s public STEMI network in a quasi-experimental design, comparing data from 2009-2010 (pre-intervention) and 2019-2020 (post-intervention). There were evaluated all confirmed STEMI cases assisted in the both periods. The interventions, implemented since 2017, included: expanding the support team, defining criteria to be a spoke, and initiating continuous education activities. The primary outcome was the rate of patients undergoing reperfusion, with secondary outcomes being time from door-to-ECG (D2E) and ECG-to-STEMI-team trigger (E2T).

Findings: Over ten years, the network's coverage increased by 300,000 individuals, and expanded by 1,800 km2. A total of 885 records were analyzed, 287 in the pre-intervention group (182 men [63·4%]; mean [SD] age 62·1 [12·5] years) and 598 in the post-intervention group (356 men [59·5%]; mean [SD] age 61.9 [11·8] years). It was noticed a substantial increase in reperfusion delivery rate (90 [31%] vs. 431 [73%]; P=·001) and reductions in time from D2E (159 [83-340] vs. 29 [15-63], P=·001), and E2T (31 [21-44] vs. 16 [6-40], P=·001).

Interpretation: The strategies adopted by Salvador’s STEMI network were associated with significant improvements in the rate of patients undergoing reperfusion and in D2E and E2T. However, the mortality rate remains high.

Funding: The work of BBA was supported by the Intramural Research Program of the Fundação Oswaldo Cruz, Brazil.

Declaration of Interest: The authors declare no conflict of interests.

Ethical Approval: Ethical approval for this study was obtained from the ethics committee Secretaria da Saúde do Estado da Bahia (CAAE: 58949416.7.00000.0052) and the declaration of Helsinki was followed. The utilization of geospatial data, population statistics, and other publicly available information did not require further authorization.

Keywords: ST-Elevation Myocardial Infarction, Reperfusion, Universal Health Care, Developing Countries, Quality Improvement

Suggested Citation

de Souza Roriz, Pollianna and Ferreira, Isabella B. B. and Pontes, Fabiana Benevides and Machado, Antônio Fernando and Aguiar, Tércio and Almeida Matos, Marcos Antônio and Paiva, Ivan and Menezes, Rodrigo C. and Andrade, Bruno B., A Decade of a Regional Network for St-Segment Elevation Myocardial Infarction Care in Brazil: Assessment of Improvements in Reperfusion Rates and Quality of Care. Available at SSRN: https://ssrn.com/abstract=4660415 or http://dx.doi.org/10.2139/ssrn.4660415

Pollianna De Souza Roriz

UNIFACS- Universidade Salvador ( email )

Isabella B. B. Ferreira

Bahiana School of Medicine and Public Health ( email )

Fabiana Benevides Pontes

Hospital Ana Nery ( email )

Antônio Fernando Machado

UNIFACS- Universidade Salvador ( email )

Tércio Aguiar

UNIFACS- Universidade Salvador ( email )

Marcos Antônio Almeida Matos

Bahiana School of Medicine and Public Health ( email )

Brazil

Ivan Paiva

Universidade Salvador (UNIFACS) ( email )

Salvador
Brazil

Rodrigo C. Menezes

Instituto de Pesquisa Clínica e Translacional ( email )

Bruno B. Andrade (Contact Author)

Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative ( email )

Oswaldo Cruz Foundation (FIOCRUZ) - Laboratório de Inflamação e Biomarcadores ( email )

Salvador
Brazil