Comparing Serum and Plasma Samples in the Performance of Commercial Igg Elisa-Based Assays for Diagnosis of Schistosoma- and Strongyloides Infection

Abstract

This study evaluated the performance of commercial ELISA-based assays for serological diagnosis of Schistosoma- and Strongyloides infection using plasma samples in comparison to serum samples. Plasma samples performed equally well to serum samples and we conclude that both sample types can be used for detection of Schistosoma- and Strongyloides antibodies.

Note:
Funding Information: This study was partly funded by a grant from the Swedish Laboratory Network for Microbiology (SLIM).

Declaration of Interests: Authors declare no conflict of interest.

Ethics Approval Statement: The study was approved by the Swedish Ethical Review Authority (2019–00430 with amendment 2020–05351).

Keywords: Enzyme-Linked Immunosorbent Assay, Serologic Tests, Plasma, Serum, Schistosoma, Strongyloides