Comparing Serum and Plasma Samples in the Performance of Commercial Igg Elisa-Based Assays for Diagnosis of Schistosoma- and Strongyloides Infection

4 Pages Posted: 4 Jun 2024

See all articles by Ioana Bujila

Ioana Bujila

affiliation not provided to SSRN

Isabelle Eliasson

affiliation not provided to SSRN

Emmeli Bång

affiliation not provided to SSRN

Anna Färnert

Karolinska Institutet - Division of Infectious Diseases

Caroline Rönnberg

affiliation not provided to SSRN

Abstract

This study evaluated the performance of commercial ELISA-based assays for serological diagnosis of Schistosoma- and Strongyloides infection using plasma samples in comparison to serum samples. Plasma samples performed equally well to serum samples and we conclude that both sample types can be used for detection of Schistosoma- and Strongyloides antibodies.

Note:
Funding Information: This study was partly funded by a grant from the Swedish Laboratory Network for Microbiology (SLIM).

Declaration of Interests: Authors declare no conflict of interest.

Ethics Approval Statement: The study was approved by the Swedish Ethical Review Authority (2019–00430 with amendment 2020–05351).

Keywords: Enzyme-Linked Immunosorbent Assay, Serologic Tests, Plasma, Serum, Schistosoma, Strongyloides

Suggested Citation

Bujila, Ioana and Eliasson, Isabelle and Bång, Emmeli and Färnert, Anna and Rönnberg, Caroline, Comparing Serum and Plasma Samples in the Performance of Commercial Igg Elisa-Based Assays for Diagnosis of Schistosoma- and Strongyloides Infection. Available at SSRN: https://ssrn.com/abstract=4848292 or http://dx.doi.org/10.2139/ssrn.4848292

Ioana Bujila (Contact Author)

affiliation not provided to SSRN ( email )

No Address Available

Isabelle Eliasson

affiliation not provided to SSRN ( email )

No Address Available

Emmeli Bång

affiliation not provided to SSRN ( email )

No Address Available

Anna Färnert

Karolinska Institutet - Division of Infectious Diseases ( email )

Sweden

Caroline Rönnberg

affiliation not provided to SSRN ( email )

No Address Available

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