Modeling and Hemodynamic Analysis Of Intracranial Aneurysms with Elastic Wall

Abstract

Intracranial aneurysm is a serious cardiovascular disease that threatens human health and hemodynamics plays an important role in the study of the growth, development and rupture of intracranial aneurysm. Due to limitations in research methods, the vascular wall of aneurysm models is usually rigidly treated. Considering the actual elastic vessel wall morphology of the aneurysm, a lattice Boltzmann model of intracranial aneurysm with elastic wall is proposed by numerical simulation to study the hemodynamic of intracranial aneurysm. In order to study the effect of wall elasticity on the intra-aneurysmal flow phenomenon, the model is used to compare and analyze the hemodynamic factors such as flow velocity, flow pattern and wall shear stress in rigid-walled aneurysm and elastic-walled aneurysm before and after intervening stent. The results indicate that the elastic walls can provide a certain buffering effect on the impact of blood flow inside the blood vessels, reducing the risk of aneurysm rupture. While the risk of rupture of real intracranial aneurysm would be magnified by the model of rigid aneurysm established by simplified method. The deformation of the elastic aneurysm could be reduced through interventional stent, reflecting the therapeutic effect of stents on aneurysms. At the same time, intervening stent diminishes the effect of compliance on intra-aneurysm hemodynamics.

Keywords: aneurysm, elastic vessel wall, numerical simulation, stent, hemodynamics