Scorerem: A User-Friendly Matlab-Gui for Rapid Eye Movement (Rem) Sleep Microstructure (Phasic/Tonic) Annotation and Quantification

Abstract

Rapid eye movement (REM) sleep plays a crucial role in memory consolidation and learning and alterations in REM sleep structure and REM sleep behaviour disorder are considered early biomarkers of neurodegenerative disorders. Due to its clinical significance, accurate quantification of REM sleep and its microstructure is increasingly pursued. To address this growing need, we introduce ScoreREM, an open-source user-friendly MATLAB graphical user interface (GUI) designed for rapid annotation and quantification of REM sleep microstructure. Due to its intuitive functionalities and vast array of potential application areas, ScoreREM will serve as an indispensable tool for rapid and accurate REM microstructure quantification in clinical studies.

Note:
Funding declaration: This work was supported by the UK Dementia Research Institute, [award number UKDRI-7005], through UK DRI Ltd, principally funded by the UK Medical Research Council, and additional funding partner Alzheimer’s Society.

Conflict of Interests: The authors declare no known competing financial or non-financial interests.

Keywords: Sleep Scoring, Automatic annotation, Rapid eye movement (REM), MATLAB