Nonlinear Device Strategy of Non-Enzyme Glucose Sensor Via Amorphous Ni Mof and Crystalline Ni3(Po4)2 Composite

Abstract

In this article, a nonlinear non-enzyme glucose sensor based on the Langmuir relationship is designed. In terms of materials, the treated Ni3+-NiMOF@Ni3(PO4)2 material has a higher surface trivalent nickel content than the NiMOF@Ni3(PO4)2 material, and this simple surface valence state adjustment engineering improves the electrochemical activity of the electrode. In terms of device performance, the glucose sensor using the above strategy exhibits a typical Langmuir relationship, and its  and  values are 1.4732 and 5.71556 × 10-4 (R2=0.99322), respectively. Furthermore, the sensitivity curve of the Ni3+-NiMOF@Ni3(PO4)2 sensor as a function of concentration was calculated by the first order differential method. The corresponding sensitivity ranges from 40.3 to 1476.7 μA mM-1 cm-2. This means that all test intervals (1-9000 μM) of the Ni3+-NiMOF@Ni3(PO4)2 sensor can serve for later embedded programming. Moreover, our work may provide some ideas for the industrialization of non-enzyme glucose sensor, it only costs about $ 80 to manufacture a device that can be used for testing in the laboratory.

Keywords: Metal Organic Framework, Ni3(PO4)2, Non-Enzyme Glucose Sensor, Amperometric Sensor, Langmuir Method