Multiphysics Modeling of Cryothermal Ablation for Cardiac Arrhythmia Treatment: A Thermal and Hemodynamic Perspective

Abstract

Cryothermal ablation is a widely used technique for the treatment of cardiac arrhythmias, offering a minimally invasive alternative to traditional surgical interventions. This study presents a comprehensive multiphysics modeling approach to analyze the thermal and hemodynamic effects of cryothermal ablation in the heart. By integrating thermal dynamics, tissue properties, and fluid flow within a computational framework, we investigate the interactions between temperature distribution, tissue damage, and blood flow during the ablation process. The model simulates the cooling and rewarming phases, highlighting the complex feedback mechanisms between the cryoprobe and surrounding myocardial tissue. Furthermore, the impact of ablation on cardiac hemodynamics, including alterations in blood flow and pressure, is examined to better understand the physiological consequences of the procedure. The results provide valuable insights into optimizing ablation protocols, improving lesion formation accuracy, and minimizing damage to surrounding tissues. This study underscores the potential of multiphysics models in advancing the precision and efficacy of cryothermal ablation for arrhythmia treatment.

Keywords: Cryothermal Ablation, Cardiac Arrhythmia, Multiphysics Modeling, Thermal Modeling, Hemodynamics, Computational Modeling, Cardiac Electrophysiology, Thermal Therapy, Ablation Techniques, Cryotherapy in Cardiology