High-Performance Non-Enzymatic Glucose Sensor Based on a Core-Sheath Wire Modified with Ni(Oh)2 and Mos2

Abstract

A non-enzymatic glucose sensor based on a core-sheath wire modified with Ni(OH)2 and MoS2 was developed. The core-sheath wire is composed of porous C/TiO2/Ti (CTNT) wire as the core and nickel hydroxide modified molybdenum disulfide nanoflowers as the sheath (Ni(OH)2-MoS2@CTNT). The core-sheath structured wire-shaped sensor demonstrates impressive performance metrics, including a sensitivity of 1718.08 μA mM−1 cm−2, a broad linear detection range of 0.001–5.813 mM, a low detection limit of 0.114 μM, and a rapid electrochemical response time of less than 2 seconds. Notably, it remains unaffected by structural analogs of glucose, such as ascorbic acid (AA), uric acid (UA), and dopamine (DA), showcasing exceptional stability, reproducibility, repeatability, and anti-interference capabilities. Validation through real sample testing revealed a spiked recovery rate of 96.70%–98.11%, further supporting its feasibility for practical applicability.

Keywords: Glucose sensor, Core-sheath, Nickel hydroxide, Molybdenum disulfide, Non-enzymatic