Towards a New Logic for Front End Management: From Drug Discovery to Drug Design in Pharmaceutical R&D

15 Pages Posted: 24 May 2007

See all articles by Maria Elmquist

Maria Elmquist

Chalmers University of Technology - Project Management

Blanche Segrestin

École Nationale Supérieure des Mines de Paris - Centre de Gestion Scientifique (CGS)

Abstract

Under pressure to innovate and be cost-effective at the same time, R&D departments are being challenged to develop new organizations and processes for Front End activities. This is especially true in the pharmaceutical industry. As drug development becomes more risky and costly, the discovery departments of pharmaceutical companies are increasingly being compelled to provide strong drug candidates for efficient development processes and quick market launches. It is argued that the Fuzzy Front End consists less of the discovery or recognition of opportunities than of the building of expanded concepts: the notion of concept generation is revisited, suggesting the need for a new logic for organizing Front End activities in order to support sustainable innovative product development. Based on an in-depth empirical study at a European pharmaceutical company, this paper contributes to improved understanding of the actual management practices used in the Front End. Using a design reasoning model (the C-K model), it also adds to the growing body of literature on the management of Front End activities in new product development processes.

Suggested Citation

Elmquist, Maria and Segrestin, Blanche, Towards a New Logic for Front End Management: From Drug Discovery to Drug Design in Pharmaceutical R&D. Creativity and Innovation Management, Vol. 16, No. 2, pp. 106-120, June 2007, Available at SSRN: https://ssrn.com/abstract=987388 or http://dx.doi.org/10.1111/j.1467-8691.2007.00424.x

Maria Elmquist (Contact Author)

Chalmers University of Technology - Project Management ( email )

SE-412 96 Goteborg
Sweden

Blanche Segrestin

École Nationale Supérieure des Mines de Paris - Centre de Gestion Scientifique (CGS) ( email )

60, boulevard Saint-Michel
Paris Cedex 06, 75272
France

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