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Vojtech Skopek

affiliation not provided to SSRN

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SCHOLARLY PAPERS

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Scholarly Papers (1)

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The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities

Number of pages: 39 Posted: 22 Jan 2026
Patrik Oleksak, David Rysanek, Marketa Vancurova, Josef Novak, Dominika Maurencova, Erika Rousarova, Jan Capek, Tomas Rousar, Karel Vales, Vojtech Skopek, Martyna Julia Maslowska, Kotryna Gumauskaite, Gabrielius Stankus, Kamil Kuca, Rudolf Andrys, Adam Skarka, Miroslav Lísa, Lukas Fresser, Sabina Surovcova, Zofia Chrienova, Martin Popr, Eugenie Nepovimova and Zdenek Hodny
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Government of the United States of America - National Institute of Mental Health, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Hradec Králové, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN
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Abstract:

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mTOR, STAT3, torkinib derivatives, anticancer drugs, cellular senescence, senotherapeutic effect