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Karel Vales

Government of the United States of America - National Institute of Mental Health

6001 Executive Boulevard, Rm. 7117, MSC 9629

Bethesda, MA 20892

United States

  • Government of the United States of America - National Institute of Mental Health

SCHOLARLY PAPERS

3

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183

TOTAL CITATIONS

0

Scholarly Papers (3)

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1.

Serotonin and Effort-Based Decision-Making: Dissociating Behavioral Effects of 8-Oh-Dpat and Pcpa

Downloads 85 (777,583)

Serotonin and Effort-Based Decision-Making: Dissociating Behavioral Effects of 8-Oh-Dpat and Pcpa

Number of pages: 26 Posted: 02 May 2024
Daniela Kunčická, Nathalie Cmarková, Simona Ondráčková, David Kačer, Daniel Bermejo Rodriguez, Karel Vales, Jan Svoboda, Hana Brožka and Aleš Stuchlík
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Government of the United States of America - National Institute of Mental Health, Government of the United States of America - National Institute of Mental Health, Government of the United States of America - National Institute of Mental Health, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN
Downloads 50 (1,095,444)

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Effort-based decision-making, hippocampus, serotonin, 8-OH-DPAT, PCPA, rat

Serotonin and Effort-Based Decision-Making: Dissociating Behavioral Effects of 8-Oh-Dpat and Pcpa

Number of pages: 26 Posted: 05 Jun 2024
Daniela Kunčická, Nathalie Cmarková, Simona Ondráčková, David Kačer, Daniel Bermejo Rodriguez, Karel Vales, Hana Brožka, Jan Svoboda and Aleš Stuchlík
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Government of the United States of America - National Institute of Mental Health, Government of the United States of America - National Institute of Mental Health, Government of the United States of America - National Institute of Mental Health, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN
Downloads 35 (1,281,607)

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Effort-based decision-making, hippocampus, serotonin, 8-OH-DPAT, PCPA, Rat

2.

Phenoxytacrine Derivatives: Low-Toxicity Neuroprotectants Exerting Affinity to Ifenprodil-Binding Site and Cholinesterase Inhibition

Number of pages: 49 Posted: 19 Dec 2023
Anna Misiachna, Barbora Svobodova, Jakub Netolicky, Marketa Chvojkova, Lenka Kleteckova, Lukas Prchal, Martin Novák, Martina Hrabinova, Tomas Kucera, Lubica Muckova, Zuzana Moravcova, Jana Zdarova Karasova, Jaroslav Pejchal, Kristina Hakenova, Barbora Hrcka Krausova, Marharyta Kolcheva, Marek Ladislav, Jan Korabecny, Jens Pahnke, Karel Vales, Martin Horak and Ondrej Soukup
Czech Academy of Sciences, University Hospital Hradec Kralove, Institute of Experimental Medicine of the CAS, National Institute of Mental Health, Czech Republic, National Institute of Mental Health, Czech Republic, University Hospital Hradec Kralove, Charles University, University Hospital Hradec Kralove, University of Defence in Brno, University Hospital Hradec Kralove, Charles University, University Hospital Hradec Kralove, University Hospital Hradec Kralove, National Institute of Mental Health, Czech Republic, Institute of Experimental Medicine of the CAS, Institute of Experimental Medicine of the CAS, Institute of Experimental Medicine of the CAS, University Hospital Hradec Kralove, University of Oslo, Government of the United States of America - National Institute of Mental Health, Czech Academy of Sciences and University Hospital Hradec Kralove
Downloads 53 (1,031,043)

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Alzheimer´s disease; electrophysiology; glutamate receptor; acetylcholinesterase; neuroprotection; in vivo; Tacrine

3.

The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities

Number of pages: 39 Posted: 22 Jan 2026
Patrik Oleksak, David Rysanek, Marketa Vancurova, Josef Novak, Dominika Maurencova, Erika Rousarova, Jan Capek, Tomas Rousar, Karel Vales, Vojtech Skopek, Martyna Julia Maslowska, Kotryna Gumauskaite, Gabrielius Stankus, Kamil Kuca, Rudolf Andrys, Adam Skarka, Miroslav Lísa, Lukas Fresser, Sabina Surovcova, Zofia Chrienova, Martin Popr, Eugenie Nepovimova and Zdenek Hodny
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Government of the United States of America - National Institute of Mental Health, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Hradec Králové, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN
Downloads 45 (1,121,190)

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mTOR, STAT3, torkinib derivatives, anticancer drugs, cellular senescence, senotherapeutic effect