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Tyler E. Jacks

Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research

77 Massachusetts Avenue

50 Memorial Drive

Cambridge, MA 02139-4307

United States

Massachusetts Institute of Technology (MIT) - Department of Biology

77 Massachusetts Ave

Building 68-132

Cambridge, MA 02139

United States

Massachusetts Institute of Technology (MIT) - Howard Hughes Medical Institute (HHMI)

31 Ames St, 68-171

Cambridge, MA

United States

SCHOLARLY PAPERS

5

DOWNLOADS

374

TOTAL CITATIONS

0

Scholarly Papers (5)

1.

Antigen Dominance Hierarchies Shape TCF1+ Progenitor CD8 T Cell Phenotypes in Tumors

Number of pages: 89 Posted: 20 Jan 2021
Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Sanofi - Massachusetts, Harvard Medical School - Department of Pathology, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, MIT McGovern Institute for Brain Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Harvard Medical School - Department of Pathology and Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research
Downloads 133 (551,165)

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TCF1; neoantigen; immunodominance; CCR6; Tc17; vaccine; lung cancer

2.

The CD155/TIGIT Axis Promotes and Maintains Immune Evasion in Neoantigen-Expressing Pancreatic Cancer

Number of pages: 79 Posted: 22 Dec 2020
Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts General Hospital Cancer Center, Broad Institute of MIT and Harvard, Broad Institute of MIT and Harvard, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research and Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research
Downloads 81 (796,622)

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3.

Longitudinal Single Cell Profiling of Regulatory T Cells Identifies IL-33 as a Driver of Tumor Immunosuppression

Number of pages: 88 Posted: 19 Mar 2019
Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Harvard Medical School, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology and Harvard University - Broad Institute, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology and Harvard University - Broad Institute, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology and Harvard University - Broad Institute, Massachusetts Institute of Technology and Harvard University - Broad Institute, Stanford University - Department of Genetics, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research and Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research
Downloads 70 (883,195)

Abstract:

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4.

Increased Dysfunction of Tumor Specific TCF-1+ CD8+ T Cells Associated with Increase in Non-Cycling TCF-1+ SlamF6- Cells Subsets Revealed by Single Cell Analysis

Number of pages: 55 Posted: 21 Oct 2020
Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Harvard University - Harvard Medical School, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology and Harvard University - Broad Institute, Massachusetts Institute of Technology and Harvard University - Broad Institute, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology and Harvard University - Broad Institute, Stanford University - Department of Genetics, Harvard Medical School - Department of Immunology, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research and Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research
Downloads 54 (1,031,043)

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T cell dysfunction, T cell subsets, TCF-1+ CD8 T cells, Lung Adenocarcinoma, T cell heterogeneity

5.

Lymphocyte Networks are Dynamic Cellular Communities in the Immunoregulatory Landscape of Lung Adenocarcinoma

Number of pages: 68 Posted: 12 Aug 2022
Sanofi - Massachusetts, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, MIT McGovern Institute for Brain Research, Harvard University - School of Engineering and Applied Sciences, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Harvard University - School of Engineering and Applied Sciences, Harvard University - Laboratory of Systems Pharmacology, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research and Harvard Medical School - Department of Pathology
Downloads 36 (1,249,711)

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multiplexed imaging, systems biology, computational biology, temporal inference, spatial analysis, spatio-temporal analysis, spatial correlation, CyCIF, fluorescence microscopy, Neoplasms, adenocarcinoma of lung, lung neoplasms, Immunotherapy, Cancer vaccines, immune checkpoint inhibitors, Programmed Cell Death 1 Receptor, animal models, Pathology, molecular pathology