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Rebecca Herbst

Harvard University - Harvard Medical School

25 Shattuck St

Boston, MA 02115

United States

  • Harvard University - Harvard Medical School

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Increased Dysfunction of Tumor Specific TCF-1+ CD8+ T Cells Associated with Increase in Non-Cycling TCF-1+ SlamF6- Cells Subsets Revealed by Single Cell Analysis

Number of pages: 55 Posted: 21 Oct 2020
Jason Schenkel, Rebecca Herbst, David Canner, Michelle Hillman, Amy Li, Olivia C. Smith, Jonathan Y. Kim, Peter Westcott, William Hwang, William Freed-Pastor, George Eng, Mike Cuoco, Patricia Rogers, Jin K. Park, Megan Burger, Orit Rozenblatt-Rosen, Le Cong, Kristen Pauken, Aviv Regev and Tyler E. Jacks
Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Harvard University - Harvard Medical School, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology and Harvard University - Broad Institute, Massachusetts Institute of Technology and Harvard University - Broad Institute, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology and Harvard University - Broad Institute, Stanford University - Department of Genetics, Harvard Medical School - Department of Immunology, Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research and Massachusetts Institute of Technology (MIT) - David H. Koch Institute for Integrative Cancer Research
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Abstract:

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T cell dysfunction, T cell subsets, TCF-1+ CD8 T cells, Lung Adenocarcinoma, T cell heterogeneity