Rafaela S. Ferreira

Federal University of Minas Gerais (UFMG) - Department of Biochemistry and Immunology

Belo Horizonte

Brazil

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Scholarly Papers (1)

1.

Carbamoyl Imidazoles As Potent, Reversible and Competitive Cruzain Inhibitors with in vitro and in vivo Trypanocidal Activity: A Structure-Based Drug Design Approach

ISCIENCE-D-19-00469
Number of pages: 115 Posted: 17 May 2019
University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, Universidade Estadual de Campinas (UNICAMP) - Institute of Chemistry, Federal University of Minas Gerais (UFMG) - Department of Biochemistry and Immunology, Universidade Estadual de Campinas (UNICAMP) - Institute of Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, University of Sao Paulo (USP), Physics Institute of Sao Carlos, Laboratory of Medicinal and Computational Chemistry, Federal University of São Paulo (Unifesp) - Department of Pharmacology, Universidade Estadual de Campinas (UNICAMP) - Institute of Chemistry and University of Sao Paulo
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Abstract:

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Chagas disease, virtual screening, organic synthesis, structure-activity relationships, drug design, drug discovery, SBDD, neglected tropical diseases