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Mark R. Cookson

Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD)

National Institutes of Health (NIH) - Cell Biology and Gene Expression Section

9000 Rockville Pike

Bethesda, MD 20892

United States

SCHOLARLY PAPERS

5

DOWNLOADS

251

TOTAL CITATIONS

6

Scholarly Papers (5)

1.

Mutations in the Sphingolipid Pathway Gene SPTLC1 are a Cause of Amyotrophic Lateral Sclerosis

Number of pages: 85 Posted: 06 Jun 2019
National Institutes of Health - Neuromuscular Diseases Research Section, National Institutes of Health - Neuromuscular Diseases Research Section, Government of the United States of America - National Institutes of Health (NIH), King’s College London - Maurice Wohl Clinical Neuroscience Institute, National Institutes of Health - Neuromuscular Diseases Research Section, National Institutes of Health - Molecular Genetics Section, National Institutes of Health - Neuromuscular Diseases Research Section, United Kingdom Dementia Research Institute Centre, National Institutes of Health - Neurodegenerative Diseases Research Unit, National Institutes of Health - Computational Biology Core, National Institutes of Health - Computational Biology Core, National Institutes of Health, Government of the United States of America - National Institutes of Health (NIH), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Johns Hopkins University - School of Medicine, Johns Hopkins University - Department of Pathology, National Institutes of Health - Neurodegenerative Diseases Research Unit, National Institutes of Health - Neurodegenerative Diseases Research Unit, National Institutes of Health - Neurodegenerative Diseases Research Unit, Uniformed Services University of the Health Sciences, United Kingdom Dementia Research Institute Centre, King’s College London - Maurice Wohl Clinical Neuroscience Institute, King’s College London - Maurice Wohl Clinical Neuroscience Institute, King’s College London - Department of Basic and Clinical Neuroscience, King’s College London - Department of Basic and Clinical Neuroscience, University of Milan - Department of Neurology and Laboratory of Neuroscience, University of Massachusetts Worcester - Department of Neurology, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’ - Unit of Genetics of Neurodegenerative and Metabolic Diseases, Macquarie University - Centre for MND Research, University of New South Wales (UNSW) - School of Medical Sciences (SoMS), University of New South Wales (UNSW) - School of Medical Sciences (SoMS), National Institutes of Health, Independent, Independent, Independent, Independent, University of Massachusetts Worcester - Department of Neurology, University of Massachusetts Worcester - Department of Neurology, University of Southampton - Faculty of Medicine, Health and Life Sciences, University of Sheffield - Sheffield Institute for Translational Neuroscience (SITraN), King’s College London - Maurice Wohl Clinical Neuroscience Institute, University of Massachusetts Worcester - Department of Neurology, ASO OIRM-S.Anna, University of Turin - Department of Neurosciences, Azienda Ospedaliera Universitaria Maggiore della Carità - ALS Center, Hebrew University of Jerusalem, King’s College London - Maurice Wohl Clinical Neuroscience Institute, University of Massachusetts Worcester - Department of Neurology, University of Massachusetts Worcester - Department of Neurology, Johns Hopkins University - Department of Pediatrics, King’s College London - Maurice Wohl Clinical Neuroscience Institute and University of Massachusetts Worcester - Department of Neurology
Downloads 112 (630,858)
Citation 4

Abstract:

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amyotrophic lateral sclerosis, genomics, de novo mutation, sphingolipid metabolism, SPTLC1, serine nutritional supplementation, deoxymethyl-sphinganine, individualized medicine

2.

Large-Scale HLA Immunopeptidome and Interactome Profiling in Microglia

Number of pages: 26 Posted: 30 Apr 2025
Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), The Translational Genomics Research Institute (TGen) - Division of Neurogenomics, Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD) and Independent
Downloads 46 (1,109,210)

Abstract:

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Microglia, Human Leukocyte Antigen, Epitopes, Immunopeptidomics, Neuroimmunology, Proteomics, Interactome

3.

Loss of LrrK2 Function Potentiates Dopamine Signaling in the Striatum to Promote Compulsive Alcohol Use

Number of pages: 49 Posted: 04 Nov 2020
National Institutes of Health (NIH) - Laboratory on Neurobiology of Compulsive Behaviors, National Institutes of Health (NIH) - Laboratory on Neurobiology of Compulsive Behaviors, National Institutes of Health (NIH) - Cell Biology and Gene Expression Section, National Institutes of Health (NIH) - Laboratory on Neurobiology of Compulsive Behaviors, University of California, San Francisco (UCSF) - Department of Neurology, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD) and National Institutes of Health (NIH) - Laboratory on Neurobiology of Compulsive Behaviors
Downloads 38 (1,209,354)
Citation 2

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4.

A Fully Automated FAIMS-DIA Mass Spectrometry-Based Proteomic Pipeline

Number of pages: 28 Posted: 27 Jan 2023
Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Yale University - Department of Pharmacology, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD) and Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD)
Downloads 32 (1,290,922)

Abstract:

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proteomics, mass spectrometry FAIMS, DIA, automation, iPSC, neurons, neurodegenerative, Alzheimer's, iNDI

5.

Application of Aligned-UMAP to Longitudinal Biomedical Studies

Number of pages: 19 Posted: 08 Dec 2022
University of Illinois at Urbana-Champaign - Department of Computer Science, University of Illinois at Urbana-Champaign - Department of Industrial and Enterprise Systems Engineering, University of Illinois at Urbana-Champaign - Department of Industrial and Enterprise Systems Engineering, Government of the United States of America - National Institute of Neurological Disorders and Stroke (NINDS), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Invicro - Image Analysis, Invicro - Image Analysis, Invicro - Image Analysis, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), University of Illinois at Urbana-Champaign - Department of Computer Science, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD) and Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD)
Downloads 23 (1,411,822)

Abstract:

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Longitudinal biomedical data, Dimensionality reduction, Unsupervised learning