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Andrew B. Singleton

Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD)

National Institute on Aging (NIA) - Molecular Genetics Section

Building 31, Room 5C27

31 Center Drive, MSC 2292

Bethesda, MD 20892

United States

SCHOLARLY PAPERS

4

DOWNLOADS

264

TOTAL CITATIONS

2

Scholarly Papers (4)

1.

Prediction, Prognosis and Monitoring of Neurodegeneration at Biobank-Scale via Machine Learning and Imaging

Number of pages: 22 Posted: 23 Feb 2024
University of Illinois at Urbana-Champaign - Department of Computer Science, National Institutes of Health, Malaysia, University of Virginia - Department of Radiology and Medical Imaging, Boston University - Department of Neurology, Institute for Neurodegenerative Disorders, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), University of Illinois at Urbana-Champaign - Department of Computer Science, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), University of Virginia - Department of Radiology and Medical Imaging and Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD)
Downloads 148 (502,974)

Abstract:

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Machine learning, neurodegenerative disorders, brain MRI imaging, early detection

2.

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

Number of pages: 84 Posted: 11 Aug 2020
National Institute on Aging - Neuromuscular Diseases Research Section, National Institutes of Health - Neuromuscular Diseases Research Section, National Institutes of Health - Computational Biology Core, Columbia University - Department of Pathology and Cell Biology, Boston University - Chronic Traumatic Encephalopathy Center, National Institutes of Health - Neuromuscular Diseases Research Section, National Institute of Neurological Disorders and Stroke - Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke - Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke - Neurodegenerative Diseases Research Unit, Queen Mary University of London - Clinical Pharmacology, Queen Mary University of London - Clinical Pharmacology, University of Massachusetts Worcester - Department of Neurology, University of Massachusetts Worcester - Department of Neurology, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’ - Division of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’ - Division of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’ - Scientific Directorate, Lund University - Division of Clinical Sciences Helsingborg, Lund University - Division of Clinical Sciences Helsingborg, Lund University - Clinical Memory Research Unit, Independent, Independent, Independent, Independent, Independent, Independent, Independent, Independent, University of Cambridge - MRC Cognition and Brain Sciences Unit, IRCCS Centro San Giovanni di Dio Fatebenefratelli - Molecular Markers Laboratory, IRCCS Centro San Giovanni di Dio Fatebenefratelli - Molecular Markers Laboratory, IRCCS Centro San Giovanni di Dio Fatebenefratelli - Molecular Markers Laboratory, University College London - Department of Molecular Neuroscience, Uniformed Services University of the Health Sciences - Department of Anatomy, Physiology and Genetics, Emory University - Department of Neurology, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), University of Massachusetts Worcester - Department of Neurology, Mayo Clinic - Department of Neuroscience, University College London - Department of Molecular Neuroscience, Scripps Translational Science Institute, National Institute on Aging - Translational Gerontology Branch, Government of the United States of America - Translational Gerontology Branch, National Institute on Aging (NIA) - Laboratory of Behavioral Neuroscience, The University of Manchester - Faculty of Human and Medical Sciences, Boston University - Department of Neurology, VA Boston Healthcare System - Department of Neurology, University College London - Department of Neurodegenerative Disease, University of Pennsylvania - Department of Pathology and Laboratory Medicine, Columbia University - Department of Pathology and Cell Biology, Columbia University - Department of Neurology, University College London - Department of Clinical and Movement Neurosciences, University College London - Department of Molecular Neuroscience, University of Massachusetts Worcester - Department of Neurology, University of Massachusetts Worcester - Department of Neurology, National Institute on Aging (NIA) - Computational Biology Group, Uniformed Services University of the Health Sciences - Department of Anatomy, Physiology and Genetics, National Institute of Neurological Disorders and Stroke - Neurodegenerative Diseases Research Unit and University of Massachusetts Worcester - Department of Neurology
Downloads 61 (951,658)
Citation 2

Abstract:

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amyotrophic lateral sclerosis, frontotemporal dementia, Lewy body dementia, Huntington’s disease, whole-genome sequencing, huntingtin, repeat expansions

3.

A Fully Automated FAIMS-DIA Mass Spectrometry-Based Proteomic Pipeline

Number of pages: 28 Posted: 27 Jan 2023
Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Yale University - Department of Pharmacology, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD) and Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD)
Downloads 32 (1,290,922)

Abstract:

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proteomics, mass spectrometry FAIMS, DIA, automation, iPSC, neurons, neurodegenerative, Alzheimer's, iNDI

4.

Application of Aligned-UMAP to Longitudinal Biomedical Studies

Number of pages: 19 Posted: 08 Dec 2022
University of Illinois at Urbana-Champaign - Department of Computer Science, University of Illinois at Urbana-Champaign - Department of Industrial and Enterprise Systems Engineering, University of Illinois at Urbana-Champaign - Department of Industrial and Enterprise Systems Engineering, Government of the United States of America - National Institute of Neurological Disorders and Stroke (NINDS), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Invicro - Image Analysis, Invicro - Image Analysis, Invicro - Image Analysis, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD), University of Illinois at Urbana-Champaign - Department of Computer Science, Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD) and Government of the United States of America - Center for Alzheimer's and Related Dementias (CARD)
Downloads 23 (1,411,822)

Abstract:

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Longitudinal biomedical data, Dimensionality reduction, Unsupervised learning