Erasmus University Rotterdam (EUR) - Department of Neurology, Erasmus University Rotterdam (EUR) - Department of Neurology, Erasmus University Rotterdam (EUR) - Department of Radiology, Erasmus University Rotterdam (EUR) - Department of Neurology, Erasmus University Rotterdam (EUR) - Department of Pathology, University of Amsterdam - Department of Pathology, University of Amsterdam - Department of Neurology, University Medical Center Utrecht - Department of Neurology and Neurosurgery, University of Amsterdam - Department of Epidemiology and Biostatistics, University Medical Center Utrecht - Department of Pathology, Erasmus University Rotterdam (EUR) - Department of Neurology, Erasmus University Rotterdam (EUR) - Department of Neurology, Erasmus University Rotterdam (EUR) - Department of Neurology, Mayo Clinic - Department of Neurology, Erasmus University Rotterdam (EUR) - Department of Pathology, University of Zurich - Department of Neurology, Heidelberg University - University Hospital Heidelberg, KU Leuven, Hôpitaux Universitaires La Pitié Salpêtrière, IRCCS Istituto delle Scienze Neurologiche di Bologna (ISNB), EORTC Headquarters, European Organisation for Research and Treatment of Cancer (EORTC), University Hospital Zurich, University of Zurich - Department of Neurology, University Medical Center Utrecht - Department of Neurology and Neurosurgery, Erasmus University Rotterdam (EUR) - Department of Pathology, Erasmus University Rotterdam (EUR) - Department of Radiology and Nuclear Medicine, University of Amsterdam - Department of Epidemiology and Biostatistics, Erasmus University Rotterdam (EUR) - Department of Pathology, University of Amsterdam - Department of Neurosurgery, Erasmus MC - Brain Tumor Centre, University of Amsterdam - University Medical Center, Erasmus University Rotterdam (EUR) - Department of Pathology and Erasmus Medical Center (MC)

University of Amsterdam - Amsterdam University Medical Centers, European Organisation for Research and Treatment of Cancer (EORTC), European Organisation for Research and Treatment of Cancer (EORTC), Leiden University, Erasmus University Rotterdam (EUR) - Erasmus Medical Center (MC), KU Leuven, Sorbonne University, Utrecht University - Department of Medical Oncology, University of Amsterdam - Amsterdam University Medical Centers, Heidelberg University - University Hospital Heidelberg, University College Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, European Organisation for Research and Treatment of Cancer (EORTC), European Organisation for Research and Treatment of Cancer (EORTC), European Organisation for Research and Treatment of Cancer (EORTC), Erasmus MC - Brain Tumor Centre and Independent

affiliation not provided to SSRN, Leiden University - Leiden University Medical Center (LUMC), Leiden University - Department of Medical Statistics, Erasmus MC - Brain Tumor Centre, Netherlands Cancer Institute - Division of Psychosocial Research and Epidemiology, affiliation not provided to SSRN, affiliation not provided to SSRN, KU Leuven, European Organisation for Research and Treatment of Cancer (EORTC), EORTC Headquarters, University of Bonn - University Hospital Bonn (UKB), University Hospital Zurich, affiliation not provided to SSRN, Université de Lille - Laboratoire Protéomique, affiliation not provided to SSRN, affiliation not provided to SSRN, Medical University of Vienna, affiliation not provided to SSRN, affiliation not provided to SSRN, International BrainTumour Alliance, IRCCS Regina Elena National Cancer Institute, affiliation not provided to SSRN, University of Amsterdam - Amsterdam University Medical Centers, affiliation not provided to SSRN, University Hospital Zurich, Universitätsklinikum Leipzig, University of Lausanne, Heidelberg University - University Hospital Heidelberg, University Hospital Zurich, Leiden University - Leiden University Medical Center (LUMC) and affiliation not provided to SSRN