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Xiangchun Li

Tianjin Medical University - National Clinical Research Center for Cancer

Tianjin

China

  • Tianjin Medical University - National Clinical Research Center for Cancer

SCHOLARLY PAPERS

7

DOWNLOADS

556

TOTAL CITATIONS

3

Scholarly Papers (7)

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1.

Scalable Batch-Correction Method for Integrating Large-Scale Single-Cell Transcriptomes

Number of pages: 51 Posted: 20 Jan 2022
Xilin Shen, Hongru Shen, Dan Wu, Mengyao Feng, Jiani Hu, Jilei Liu, Yichen Yang, Meng Yang, Yang Li, Lei Shi, Kexin Chen and Xiangchun Li
Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - Key Laboratory of Cancer Prevention and Therapy and Tianjin Medical University - National Clinical Research Center for Cancer
Downloads 163 (459,428)

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single-cell, batch-correction, data integration.

2.

Analysis of Immune-Related Signatures of Lung Adenocarcinoma Identifies Two Distinct Immunophenotypic Subtypes: Implications for Immune Checkpoint Blockade Therapy

Number of pages: 25 Posted: 15 Aug 2019
Qinghua Wang, Meng Yang, Yichen Yang, Fengju Song, Xiangchun Li and Kexin Chen
Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Tianjin Medical University - Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University - Department of Epidemiology and Biostatistics, Tianjin Medical University - National Clinical Research Center for Cancer and Tianjin Medical University - Key Laboratory of Cancer Prevention and Therapy
Downloads 151 (491,334)
Citation 2

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lung adenocarcinoma; immune subtyping; immunotherapy; prognosis

3.

Immunological and Clinical Immunotherapy Implications of NLRP3 Mutations in Melanoma

Number of pages: 23 Posted: 15 Oct 2020
Qinghua Wang, Juncheng Lyu, Fuyan Shi, Yanfeng Ren, Qian Mao, Yujie Liu, Ting Li, Xiangchun Li and Suzhen Wang
Department of Health Statistics, School of Public Health, Weifang Medical University, Department of Health Statistics, School of Public Health, Weifang Medical University, Baogang Hospital of Inner Mongolia, Department of Health Statistics, School of Public Health, Weifang Medical University, Department of Health Statistics, School of Public Health, Weifang Medical University, Department of Health Statistics, School of Public Health, Weifang Medical University, Department of Bone and Soft Tissue Tumor, Tianjin Medical University, Tianjin Medical University - National Clinical Research Center for Cancer and Weifang Medical University - Department of Health Statistics
Downloads 81 (796,622)

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Melanoma, Immunotherapy, NLRP3 mutations, predictive indicator

4.

High Mutation Load, Immune-Activated Microenvironment, Favorable Outcome and Better Immunotherapeutic Efficacy of Patients with Melanoma Harboring MUC16/CA125 Mutation

Number of pages: 25 Posted: 30 Jan 2020
Qing-Hua Wang, Yi-Chen Yang, Meng Yang, Xiangchun Li and Kexin Chen
Tianjin Medical University - Department of Epidemiology and Biostatistics, Tianjin Medical University - National Clinical Research Center for Cancer, Tianjin Medical University - National Clinical Research Center for Cancer, Tianjin Medical University - National Clinical Research Center for Cancer and Tianjin Medical University - Key Laboratory of Cancer Prevention and Therapy
Downloads 53 (1,031,043)
Citation 1

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MUC16; tumor mutation load; immune microenvironment; survival outcome; immunotherapeutic efficacy; melanoma

5.

Tumor Specific Methylome in Chinese High-Grade Serous Ovarian Cancer Characterized by Gene Expression Profile and Tumor Genotype

Number of pages: 46 Posted: 06 Dec 2019
Fangfang Song, Lian Li, Baifeng Zhang, Yanrui Zhao, Hong Zheng, Meng Yang, Xiangchun Li, Jing Tian, Caiyun Huang, Luyang Liu, Qinghua Wang, Wei Zhang and Kexin Chen
Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Beijing Genomics Institute (BGI), Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Tianjin Medical University - National Clinical Research Center for Cancer, Tianjin Medical University - Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology - Department of Epidemiology and Biostatistics, Wake Forest Baptist Medical Center and Tianjin Medical University - Key Laboratory of Cancer Prevention and Therapy
Downloads 48 (1,097,529)

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HGSOC; Tissue specific DNA methylation; Integrative analysis; Regulation of RNA expression; TP53 mutation

6.

HTATSF1-Nucleated PARylation and Phosphorylation Cascade Dictates Homologous Recombination and Modulates Chemotherapeutic Response of Breast Carcinoma

Number of pages: 107 Posted: 05 Oct 2021
Jiao Zhao, Shanshan Tian, Qiushi Guo, Jieyou Zhang, Guohui Yu, Xiaodan Wang, Xilin Shen, Ying Yang, Ling Liu, Xiangchun Li, Jihui Hao, Na Yang, Ding Ai, Jie Yang, Jie Yang, Zhi Yao, Shuai Ma, Kai Zhang and Lei Shi
Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Southern Medical University, Nankai University - State Key Laboratory of Medicinal Chemical Biology, Tianjin Medical University - Tianjin Cancer Institute, Capital Medical University - Core Facilities Center, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - National Clinical Research Center for Cancer, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Nankai University - State Key Laboratory of Medicinal Chemical Biology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - Department of Biochemistry and Molecular BiologyTianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology and Tianjin Medical University - State Key Laboratory of Experimental Hematology
Downloads 44 (1,133,231)

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homologous recombination, DNA double-strand break (DSB), genome stability, TOPBP1 loading, RPA-RAD51 exchange, PARPi, breast cancer

7.

Guideline-grounded Agentic AI Enables Reliable Report-level Diagnostic Reasoning in Oncologic Pathology

Number of pages: 44 Posted: 09 Jun 2026
Xilin Shen, Rui Kong, Yong Wang, Yiping Xiang, Meilin Sun, Manlin Yang, Kexin Chen, Xiangchun Li and Yan Sun
Tianjin Medical University - Tianjin Cancer Institute, Tianjin Medical University - Department of Pathology, Tianjin Medical University - Department of Pathology, Tianjin Medical University - Department of Pathology, Tianjin Medical University - Department of Pathology, Tianjin Medical University - Department of Pathology, Tianjin Medical University - Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University - National Clinical Research Center for Cancer and Tianjin Medical University - Department of Pathology
Downloads 16

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Agentic AI, large language models, retrieval-augmented generation, Computational Pathology, Diagnostic Decision Support, Oncologic Pathology