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Shuai Ma

Tianjin Medical University - State Key Laboratory of Experimental Hematology

Tianjin, 300060

China

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HTATSF1-Nucleated PARylation and Phosphorylation Cascade Dictates Homologous Recombination and Modulates Chemotherapeutic Response of Breast Carcinoma

Number of pages: 107 Posted: 05 Oct 2021
Jiao Zhao, Shanshan Tian, Qiushi Guo, Jieyou Zhang, Guohui Yu, Xiaodan Wang, Xilin Shen, Ying Yang, Ling Liu, Xiangchun Li, Jihui Hao, Na Yang, Ding Ai, Jie Yang, Jie Yang, Zhi Yao, Shuai Ma, Kai Zhang and Lei Shi
Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Southern Medical University, Nankai University - State Key Laboratory of Medicinal Chemical Biology, Tianjin Medical University - Tianjin Cancer Institute, Capital Medical University - Core Facilities Center, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - National Clinical Research Center for Cancer, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Nankai University - State Key Laboratory of Medicinal Chemical Biology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - Department of Biochemistry and Molecular BiologyTianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology, Tianjin Medical University - State Key Laboratory of Experimental Hematology and Tianjin Medical University - State Key Laboratory of Experimental Hematology
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Abstract:

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homologous recombination, DNA double-strand break (DSB), genome stability, TOPBP1 loading, RPA-RAD51 exchange, PARPi, breast cancer