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Stephen John Hill

University of Nottingham - Division of Physiology

United Kingdom

University of Nottingham - Cell Signalling Research Group

SCHOLARLY PAPERS

5

DOWNLOADS

168

TOTAL CITATIONS

0

Scholarly Papers (5)

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1.

Monitoring Ligand-Induced Changes in Receptor Conformation with NanoBiT Conjugated Nanobodies

Number of pages: 40 Posted: 21 Apr 2020
Mark Soave, Raimond Heukers, Barrie Kellam, Jeanette Woolard, Martine J. Smit, Stephen J. Briddon and Stephen John Hill
University of Nottingham - Division of Physiology, VU University Amsterdam, University of Nottingham, University of Nottingham - Division of Physiology, VU University Amsterdam, University of Nottingham - Division of Physiology and University of Nottingham - Division of Physiology
Downloads 61 (951,658)

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Nanobodies, chemokine receptor, CXCR4, NanoBiT, NanoLuciferase, conformational selectivity, extracellular loop 2.

2.

Probing the Binding of Interleukin-23 to Individual Receptor Components and the IL23 Heteromeric Receptor Complex in Living Cells Using NanoBRET

Number of pages: 48 Posted: 08 Jan 2021
Charles S. Lay, Angela Bridges, Joelle Goulding, Stephen J. Briddon, Zoja Soloviev, Peter D. Craggs and Stephen John Hill
University of Nottingham - Division of Physiology, GlaxoSmithKline - Protein and Cellular Sciences, University of Nottingham - Division of Physiology, University of Nottingham - Division of Physiology, GlaxoSmithKline - Protein and Cellular Sciences, GlaxoSmithKline - Medicine Design, Medicinal Science and Technology and University of Nottingham - Division of Physiology
Downloads 34 (1,263,436)

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Interleukin-23, IL23R, IL12Rβ1, cytokine receptor, receptor oligomerisation, IL23p19, IL12p40, NanoBRET, ligand-binding

3.

The Interleukin-23 Receptor Exists as a Heteromer of IL2Rβ1 and IL23R Under Basal Conditions and Does Not Undergo Ligand-Induced Dimerization on Activation by Cytokine

Number of pages: 29 Posted: 07 Feb 2022
Charles Lay, Peter D. Craggs and Stephen John Hill
University of Nottingham - Division of Physiology, GlaxoSmithKline - Medicine Design, Medicinal Science and Technology and University of Nottingham - Division of Physiology
Downloads 28 (1,345,526)

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Interleukin-23, IL23R, IL12Rβ1, cytokine receptor, receptor oligomerisation, IL23p19, IL12p40, NanoBRET, NanoBiT

4.

NanoB 2: Monitoring Interactions of Ligands with Membrane Proteins by Combining Nanobodies and NanoBRET

Number of pages: 116 Posted: 23 Dec 2022
Jelle van den Bor, Nick Bergkamp, Stephanie M. Anbuhl, Françoise Dekker, Dehan Comez, Claudia V. Perez Almeria, Reggie Bosma, Carl W. White, Laura E. Kilpatrick, Stephen John Hill, Marco Siderius, Martine Smit and Raimond Heukers
VU University Amsterdam - Division of Medicinal Chemistry, VU University Amsterdam - Division of Medicinal Chemistry, VU University Amsterdam - Division of Medicinal Chemistry, VU University Amsterdam - Division of Medicinal Chemistry, University of Nottingham - Cell Signalling Research Group, VU University Amsterdam - Division of Medicinal Chemistry, VU University Amsterdam - Division of Medicinal Chemistry, University of Nottingham - Cell Signalling Research Group, University of Nottingham - Division of Bimolecular Science and Medicinal Chemistry, University of Nottingham - Division of Physiology, VU University Amsterdam - Division of Medicinal Chemistry, VU University Amsterdam - Division of Medicinal Chemistry and VU University Amsterdam - Division of Medicinal Chemistry
Downloads 23 (1,411,822)

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GPCRs, RTKs, membrane receptors, NanoBRET, binding, nanobodies, real-time, homogenous, therapeutic potential, fluorescent probes

5.

Probing Ligand-Induced Changes in Cell Surface Expression of E-Selectin Using CRISPR/Cas9-Mediated Protein Tagging with HiBiT in Primary Human Endothelial Cells

Number of pages: 33 Posted: 27 Dec 2022
Lydia Ogrodzinski, Simon Platt, Cameron Alexander, Tracy D. Farr, Jeanette Woolard, Stephen John Hill and Laura E. Kilpatrick
University of Nottingham - Division of Physiology, University of Nottingham - Division of Physiology, University of Nottingham - Division of Molecular Therapeutics and Formulation, University of Nottingham - Division of Physiology, University of Nottingham - Division of Physiology, University of Nottingham - Division of Physiology and University of Nottingham - Division of Bimolecular Science and Medicinal Chemistry
Downloads 22 (1,424,331)

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NanoLuc, NanoBiT, E-selectin, Inflammatory mediators, E-selectin binding peptide