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Stephen J. Briddon

University of Nottingham - Division of Physiology

United Kingdom

  • University of Nottingham - Division of Physiology

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Probing the Binding of Interleukin-23 to Individual Receptor Components and the IL23 Heteromeric Receptor Complex in Living Cells Using NanoBRET

Number of pages: 48 Posted: 08 Jan 2021
Charles S. Lay, Angela Bridges, Joelle Goulding, Stephen J. Briddon, Zoja Soloviev, Peter D. Craggs and Stephen John Hill
University of Nottingham - Division of Physiology, GlaxoSmithKline - Protein and Cellular Sciences, University of Nottingham - Division of Physiology, University of Nottingham - Division of Physiology, GlaxoSmithKline - Protein and Cellular Sciences, GlaxoSmithKline - Medicine Design, Medicinal Science and Technology and University of Nottingham - Division of Physiology
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Abstract:

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Interleukin-23, IL23R, IL12Rβ1, cytokine receptor, receptor oligomerisation, IL23p19, IL12p40, NanoBRET, ligand-binding