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Luis Damasceno

affiliation not provided to SSRN

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Scholarly Papers (1)

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Targeting Dihydroorotate Dehydrogenase (Dhodh) for Host-Directed Therapy: Discovery of a Novel Alkyne-Based Scaffold Inhibitor Effective Against Sars-Cov-2

Number of pages: 64 Posted: 28 Jan 2025
Flavio da Silva Emery, Miguel M. Vaidergorn, Aline D. Purificação, Pedro I. P. Leite, Sabrina Silva-Mendonça, Wemenes J. L. Silva, Thiago dos Santos, Daniel Gedder Silva, Bruna Fleck Godoi, Carolina Sacramento, Mayara Mattos, Natalia Fintelman-Rodrigues, Caroline S. Freitas, Luis Damasceno, Yoko Shishikura, Alex Brown, Karolina Wrobel, Jennifer Riley, Thiago Souza, Kevin D. Read, Jose Alves-filho, Carolina H. Andrade and Maria Cristina Nonato
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Federal University of Goias, Federal University of Goias, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Oswaldo Cruz Foundation (FIOCRUZ), Fundação Oswaldo Cruz - Instituto Oswaldo Cruz, Oswaldo Cruz Foundation (FIOCRUZ), Fundação Oswaldo Cruz - Instituto Oswaldo Cruz, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Oswaldo Cruz Foundation (FIOCRUZ), affiliation not provided to SSRN, University of São Paulo (USP), Federal University of Goias and affiliation not provided to SSRN
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Abstract:

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Dihydroorotate dehydrogenase, fragments, antiviral, host-directed therapy, diarylethines