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John Mascola

National Institutes of Health - Vaccine Research Center

Bethesda, MD 20892-9806

United States

SCHOLARLY PAPERS

5

DOWNLOADS

190

TOTAL CITATIONS

4

Scholarly Papers (5)

1.

Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

Number of pages: 65 Posted: 26 Oct 2020
National Institutes of Health - Vaccine Research Center, Frederick National Laboratory for Cancer Research - Electron Microscopy Laboratory, National Institutes of Health - Vaccine Research Center, Columbia University - Department of Biochemistry and Molecular Biophysics, Columbia University - Department of Biochemistry and Molecular Biophysics, National Institutes of Health - Vaccine Research Center, Columbia University - Department of Biochemistry and Molecular Biophysics, Columbia University - Department of Biochemistry and Molecular Biophysics, Johns Hopkins University - Department of Biology, Columbia University - Department of Biochemistry and Molecular Biophysics, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Frederick National Laboratory for Cancer Research - Electron Microscopy Laboratory, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Columbia University - Aaron Diamond AIDS Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Columbia University - Department of Chemistry, Columbia University - Aaron Diamond AIDS Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center and National Institutes of Health - Vaccine Research Center
Downloads 48 (1,097,529)
Citation 2

Abstract:

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ACE2 receptor, endosomal entry, pH-dependent switch, receptor-binding domain (RBD), structural rearrangement, type 1 fusion machine

2.

Molecular Dissection Of Human Antibody Responses Following Prefusion-Stabilized RSV F Vaccination

Number of pages: 58 Posted: 28 Oct 2020
National Institutes of Health - Vaccine Research Center, University of Texas at Austin - Department of Molecular Biosciences, National Institutes of Health - Vaccine Research Center, University of Texas at Austin - Department of Molecular Biosciences, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, University of Texas at Austin - Department of Molecular Biosciences, University of Kansas - Department of Pharmaceutical Chemistry, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, University of Kansas - Bioengineering Graduate Program, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, University of Texas at Austin - Department of Molecular Biosciences and National Institutes of Health - Vaccine Research Center
Downloads 45 (1,133,231)

Abstract:

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Respiratory syncytial virus (RSV), Fusion glycoprotein (F), memory B cells, neutralizing antibodies, antibody repertoire, public clonotypes, cryo-EM structure

3.

Potent Anti-Viral Activity of a Trispecific HIV Antibody in SHIV-Infected Monkeys

Number of pages: 57 Posted: 02 Aug 2021
National Institutes of Health - Vaccine Research Center, Sanofi - Massachusetts, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, Government of the United States of America - AIDS and Cancer Virus Program, Government of the United States of America - Vaccine Research Center, Sanofi - Massachusetts, Sanofi - Massachusetts, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, University of Pennsylvania - Perelman School of Medicine, University of Pennsylvania - Perelman School of Medicine, National Institutes of Health - Vaccine Research Center, affiliation not provided to SSRN, National Institutes of Health - Vaccine Research Center, Frederick National Laboratory for Cancer Research - AIDS and Cancer Virus Program, Government of the United States of America - AIDS and Cancer Virus Program, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Sanofi - Massachusetts, Sanofi and National Institutes of Health - Vaccine Research Center
Downloads 35 (1,263,436)
Citation 1

Abstract:

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4.

Vaccination Induces Maturation of Diverse Unmutated VRC01-Class Precursors to HIV-1 Broadly Neutralizing Antibodies in an Ig-Humanized Mouse Model

Number of pages: 156 Posted: 15 Sep 2020
National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Columbia University - Aaron Diamond AIDS Research Center, National Institutes of Health - Vaccine Research Center, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Boston Children’s Hospital - Program in Cellular and Molecular Medicine, Boston Children’s Hospital - Program in Cellular and Molecular Medicine, National Institutes of Health - Vaccine Research Center and National Institutes of Health - Vaccine Research Center
Downloads 34 (1,277,121)

Abstract:

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antibody VRC01, broadly neutralizing antibody, HIV-1 vaccine, somatic hypermutations

5.

A Structure-Based Matrix Approach Yields Improved VRC01-Class Antibodies for HIV-1 Therapy and Prevention

Number of pages: 41 Posted: 05 Oct 2020
National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health (NIH) - Laboratory of Immunoregulation, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, Government of the United States of America - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health - Vaccine Research Center, National Institutes of Health (NIH) - Vaccine Research Center, Independent, National Institutes of Health - Vaccine Research Center, National Institutes of Health (NIH) - Vaccine Research Center, National Institutes of Health - Viral Pathogenesis Section, National Institutes of Health - Vaccine Research Center and National Institutes of Health - Vaccine Research Center
Downloads 28 (1,359,097)
Citation 1

Abstract:

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antibody VRC01, broadly neutralizing antibody, HIV-1 envelope trimer, polyreactivity, prophylaxis, treatment