University of Washington, Columbia University, Boston University - Chobanian & Avedisian School of Medicine, University of Washington, Virginia Mason Medical Center - Benaroya Research Institute, Rho Inc., Rho Inc., University of Texas at Dallas - Southwestern Medical Center, University of Texas at Dallas - Southwestern Medical Center, University of Colorado, Aurora - Children’s Hospital Colorado, Columbia University - Division of Pediatric Pulmonology, Ann & Robert H. Lurie Children’s Hospital of Chicago, Cincinnati Children's Hospital Medical Center, Cincinnati Children's Hospital Medical Center, Henry Ford Health System, Children's National Hospital, Vanderbilt University, Government of the United States of America - National Institutes of Health (NIH), Government of the United States of America - National Institutes of Health (NIH), Government of the United States of America - National Institutes of Health (NIH), Government of the United States of America - National Institutes of Health (NIH), University of Wisconsin-Madison - School of Medicine and Public Health, University of Wisconsin-Madison - School of Medicine and Public Health, University of Wisconsin-Madison - School of Medicine and Public Health and affiliation not provided to SSRN

Rowan University, Vanderbilt University, Vanderbilt University, Vanderbilt University, Rowan University, Henry Ford Health System - Center for Allergy and Immunology, Marshfield Clinic Research Institute, Rho Inc., Rho Inc., Government of the United States of America - National Institutes of Health (NIH), Rho Inc., Vanderbilt University, Harvard University - Massachusetts General Hospital, Henry Ford Health System, University of Colorado, University of Texas at Dallas - Southwestern Medical Center, Northwestern University, Cincinnati Children's Hospital Medical Center, University of Wisconsin-Madison - School of Medicine and Public Health, Columbia University, University of Colorado, Aurora - Children’s Hospital Colorado, Boston University - Chobanian & Avedisian School of Medicine, Washington University in St. Louis, Harvard University - Harvard Medical School, Cincinnati Children's Hospital Medical Center - Division of Allergy and Immunology, National Jewish Health, University of Wisconsin-Madison, Children's National Hospital, Henry Ford Health System, Government of the United States of America - National Institutes of Health (NIH) and Vanderbilt University

University of Washington, University of Washington, Benaroya Research Institute, Benaroya Research Institute, Rho Inc., Columbia University, University of Texas at Dallas - Southwestern Medical Center, Washington University in St. Louis, University of Colorado, Aurora - Children’s Hospital Colorado, Cincinnati Children's Hospital Medical Center, Cincinnati Children's Hospital Medical Center, Ann & Robert H. Lurie Children’s Hospital of Chicago, Ann & Robert H. Lurie Children’s Hospital of Chicago, University of Texas at Dallas - Southwestern Medical Center, Boston University - Chobanian & Avedisian School of Medicine, Henry Ford Health System, Children's National Hospital, University of California, San Francisco - Division of Gastroenterology and Hepatology, University of Washington, Government of the United States of America - National Institute of Allergy and Infectious Diseases, Government of the United States of America - National Institutes of Health (NIH), University of Wisconsin-Madison - School of Medicine and Public Health, Vanderbilt University, University of Wisconsin-Madison - School of Medicine and Public Health and University of Wisconsin-Madison - School of Medicine and Public Health

Harvard University - Cardiovascular Research Institute, National Jewish Health, Helmholtz Association of German Research Centres - German Research Centre for Environmental Health, Lovelace Respiratory Research Institute, University of North Carolina (UNC) at Chapel Hill - Department of Pathology and Laboratory Medicine, University of Virginia - Center for Public Health Genomics, Harvard University - Cardiovascular Research Institute, Harvard University - Cardiovascular Research Institute, Harvard University - Cardiovascular Research Institute, National Jewish Health, Boston University School of Public Health - Department of Biostatistics, AstraZeneca - Translational Science and Experimental Medicine, Helmholtz Association of German Research Centres - German Research Centre for Environmental Health, Weill Cornell Medicine in Qatar - Department of Physiology and Biophysics, Max Planck Institute for Heart and Lung Research - Biomolecular Mass Spectrometry, University of Washington - Department of Biostatistics, University of Washington - Department of Biostatistics, University of Vermont - Department of Pathology and Laboratory Medicine, UCLA Medical Center - The Institute for Translational Genomics and Population Sciences, Duke University - Duke Molecular Physiology Institute, University of Washington - Department of Biostatistics, University of Vermont - Department of Pathology and Laboratory Medicine, University of Vermont - Department of Pathology and Laboratory Medicine, UCLA Medical Center - The Institute for Translational Genomics and Population Sciences, Government of the United States of America - National Heart, Lung and Blood Institute, University of Virginia - Center for Public Health Genomics, UCLA Medical Center - The Institute for Translational Genomics and Population Sciences, University of Nebraska at Omaha, University of Michigan at Ann Arbor, University of California, San Francisco (UCSF) - Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of Iowa, Carver College of Medicine, Department of Internal Medicine, Harvard University - Channing Division of Network Medicine, National Jewish Health, Boston University School of Public Health - Department of Biostatistics, Boston University - Preventive Medicine and Epidemiology, University of Texas Southwestern Medical Center - Department of Medicine, Beth Israel Deaconess Medical Center - Division of Cardiovascular Medicine, Boston University - Chobanian & Avedisian School of Medicine, Columbia University - Irving Medical Center, University of North Carolina (UNC) at Chapel Hill - Department of Biostatistics, Boston University - Department of Biostatistics, University of Virginia - Center for Public Health Genomics, University of North Carolina (UNC) at Chapel Hill, Harvard University - Division of Pulmonary and Critical Care Medicine, Helmholtz Association of German Research Centres - German Research Centre for Environmental Health and National Jewish Health - Department of Medicine

Government of the United States of America - National Heart, Lung, and Blood Institute, Harvard University - Channing Division of Network Medicine, Government of the United States of America - National Heart, Lung, and Blood Institute, University of Southern California - Methylation Characterization Center, Government of the United States of America - National Heart, Lung, and Blood Institute, Government of the United States of America - National Heart, Lung, and Blood Institute, Government of the United States of America - National Heart, Lung, and Blood Institute, Boston University - Pulmonary Center, Government of the United States of America - National Heart, Lung, and Blood Institute, Government of the United States of America - National Heart, Lung, and Blood Institute, Government of the United States of America - National Heart, Lung, and Blood Institute, Harvard Medical School - Channing Division of Network Medicine, Boston University - Chobanian & Avedisian School of Medicine, Government of the United States of America - National Heart, Lung, and Blood Institute and Harvard University - Channing Division of Network Medicine