default author photo

Mark Minden

University of Toronto - Princess Margaret Cancer Centre

610 University Avenue

Toronto, ON M5G 2M9

Canada

  • University of Toronto - Princess Margaret Cancer Centre

SCHOLARLY PAPERS

2

DOWNLOADS

66

TOTAL CITATIONS

0

Scholarly Papers (2)

Actions:
Email selected abstracts
1.

Nicotinamide Phosphoribosyltransferase Inhibitors Selectively Induce Apoptosis of AML Stem Cells by Disrupting Lipid Homeostasis

Number of pages: 78 Posted: 20 Oct 2020
Amit Subedi, Qiang Liu, David Sharon, Severine Cathelin, Changjiang Xu, Veronique Voisin, Gary D. Bader, Angelo D’Alessandro, Eric R. Lechman, John E. Dick, Mark Minden, Jean C. Y. Wang and Steven M. Chan
University Health Network - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Department of Molecular Genetics, University of Colorado, Aurora - Department of Biochemistry and Molecular Genetics, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre and University of Toronto - Princess Margaret Cancer Centre
Downloads 40 (1,183,237)

Abstract:

Loading...

acute myeloid leukemia, leukemic stem cells, drug screen, Metabolism, NAMPT, NAD metabolism, SREBP signaling, lipotoxicity, fatty acid, dipyridamole, drug combination

2.

RKI-1447, a ROCK Inhibitor, Targets SRSF2 Mutated Leukemia by Disrupting Cell Mitosis and Nuclear Morphology

Number of pages: 69 Posted: 05 Jul 2023
Minhua Su, Tom Fleisher, Inna Grosheva, Melanie Bokstad Horev, Malgorzata Olszewska, Camilla Ciolli Mattioli, Haim Barr, Alexander Plotnikov, Silvia Carvalho, Yoni Moskovich, Mark Minden, Noa Chapal-Ilani, Eirini P. Papapetrou, Nili Dezorella, Tao Cheng, Nathali Kaushansky, Benjamin Geiger and Liran I. Shlush
Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - State Key Laboratory of Experimental Hematology, Weizmann Institute of Science - Department of Molecular and Cellular Biology, Weizmann Institute of Science - Department of Immunology, Weizmann Institute of Science - Department of Immunology, Mount Sinai Health System - Department of Oncological Sciences, Weizmann Institute of Science - Department of Immunology, Weizmann Institute of Science - Nancy and Stephen Grand Israel National Center for Personalized Medicine (INCPM), Weizmann Institute of Science - Nancy and Stephen Grand Israel National Center for Personalized Medicine (INCPM), Weizmann Institute of Science - Nancy and Stephen Grand Israel National Center for Personalized Medicine (INCPM), Weizmann Institute of Science - Department of Molecular and Cellular Biology, University of Toronto - Princess Margaret Cancer Centre, Weizmann Institute of Science - Department of Molecular and Cellular Biology, Mount Sinai Health System - Icahn School of Medicine, Weizmann Institute of Science - Electron Microscopy Unit, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - State Key Laboratory of Experimental Hematology, Weizmann Institute of Science - Department of Molecular and Cellular Biology, Weizmann Institute of Science - Department of Immunology and Weizmann Institute of Science - Department of Molecular and Cellular Biology
Downloads 26 (1,372,601)

Abstract:

Loading...

SRSF2, Cytoskeleton, ROCK, Nuclear morphology