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Robert G. Croy

Massachusetts Institute of Technology (MIT) - Department of Biological Engineering

77 Massachusetts Avenue

50 Memorial Drive

Cambridge, MA 02139-4307

United States

  • Massachusetts Institute of Technology (MIT) - Department of Biological Engineering

SCHOLARLY PAPERS

2

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Scholarly Papers (2)

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1.

A Synthetic Agent Ameliorates Polycystic Kidney Disease by Promoting Apoptosis of Cystic Cells Through Increased Oxidative Stress

Number of pages: 57 Posted: 25 Oct 2021
Bogdan I. Fedeles, Sorin V. Fedeles, Yasunobu Ishikawa, Sakunchai Khumsubdee, Matteus Krappitz, Nina Gubina, Denise C. Andrade, Parisa Westergerling, Tobias Staudner, Jake Campolo, Sally S. Liu, Ke Dong, Yiqiang Cai, Anna Rachel Gallagher, Somsak Ruchirawat, Robert G. Croy, John M. Essigmann and Stefan Somlo
Massachusetts Institute of Technology - Departments of Biological Engineering, Chemistry and Center for Environmental Health Sciences, Yale University - Section of Nephrology, Yale University - Section of Nephrology, Massachusetts Institute of Technology (MIT), Yale University - Section of Nephrology, Massachusetts Institute of Technology (MIT), Massachusetts Institute of Technology (MIT), Yale University - Section of Nephrology, Yale University - Section of Nephrology, Massachusetts Institute of Technology (MIT), Massachusetts Institute of Technology (MIT), Yale University - Section of Nephrology, Yale University - Section of Nephrology, Yale University - Section of Nephrology, Chulabhorn Research Institute, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Massachusetts Institute of Technology - Departments of Biological Engineering, Chemistry and Center for Environmental Health Sciences and Yale University - Section of Nephrology
Downloads 61 (961,006)

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PKD, mouse model, cystic disease, drug discovery, target validation, lead optimization, oxidative stress, apoptosis

2.

Excision of Mutagenic Replication-Blocking Lesions Suppresses Cancer But Promotes Cytotoxicity and Lethality in Nitrosamine-Exposed Mice

Number of pages: 52 Posted: 02 Nov 2020
Jennifer Elizabeth Kay, Joshua J. Corrigan, Amanda L. Armijo, Ilana S. Nazari, Ishwar N. Kohale, Dorothea K. Torous, Svetlana L. Avlasevich, Robert G. Croy, Dushan N. Wadduwage, Sebastian E. Carrasco, Stephen D. Dertinger, Forest M. White, John M. Essigmann, Leona D. Samson and Bevin P. Engelward
Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Litron Laboratories, Litron Laboratories, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Harvard University - The John Harvard Distinguished Science Fellows Program, Massachusetts Institute of Technology - Division of Comparative Medicine, Litron Laboratories, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Massachusetts Institute of Technology - Departments of Biological Engineering, Chemistry and Center for Environmental Health Sciences, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering and Massachusetts Institute of Technology (MIT) - Department of Biological Engineering
Downloads 34 (1,277,121)

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alkyladenine glycosylase, DNA damage, replication blocking lesion, DNA strand break, nitrosamine, cancer, mutation, liver