Columbia University - Center for Translational and Systems Neuroimmunology, Columbia University - Center for Translational and Systems Neuroimmunology, Roche - Neuroscience and Rare Diseases (NRD), Columbia University - Irving Medical CenterColumbia University - Center for Translational and Systems Neuroimmunology, Columbia University - Irving Medical CenterColumbia University - Columbia Multiple Sclerosis Center, Roche - gRED OMNI-Biomarker Development, Roche - Product Development Medical Affairs (PDMA) Neuroscience, University of Basel - Department of Neurology and Biomedicine, Roche - Neuroscience and Rare Diseases (NRD), Columbia University - Irving Medical CenterColumbia University - Center for Translational and Systems Neuroimmunology, Columbia University - Irving Medical CenterColumbia University - Center for Translational and Systems Neuroimmunology, University of Basel - Department of Neurology and Biomedicine, Columbia University - Center for Translational and Systems Neuroimmunology and Roche - Neuroscience and Rare Diseases (NRD)Roche - Neuroscience and Rare Diseases (NRD)