University of Milan - Department of Pathophysiology and Transplantation, University of Milan - Department of Pathophysiology and Transplantation, University of Gothenburg - Department of Molecular and Clinical Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - General Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Department of Transfusion Medicine and Hematology, University of Gothenburg - Department of Molecular and Clinical Medicine, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico - General Medicine and Metabolic Diseases, University of Gothenburg - Department of Molecular and Clinical Medicine, Università degli Studi di Milano - Department of Pathophysiology and Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Scientific Direction, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Division of Gastroenterology and Hepatology, - Section of Gastroenterology and Hepatology, Università Cattolica di Roma - Department of Internal Medicine, Campus Bio-Medico University - Clinical Medicine and Hepatology Unit, University of Campania “Luigi Vanvitelli” - Division of Hepatogastroenterology, University of Eastern Finland - Institute of Public Health and Clinical Nutrition, Università di Torino - Department of Medical Sciences, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Department of Pathophysiology and Transplantation, Newcastle University - Translational and Clinical Research Institute, Università degli Studi di Udine - Clinic of Internal Medicine – Liver Unit, Università degli Studi di Milano - Department of Pathophysiology and Transplantation, Independent, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - General Medicine and Metabolic Diseases and University of Milan - Department of Pathophysiology and Transplantation