default author photo

Nicholas T. Seyfried

Emory University - Department of Biochemistry

201 Dowman Drive

Atlanta, GA 30322

United States

SCHOLARLY PAPERS

5

DOWNLOADS

340

TOTAL CITATIONS

0

Scholarly Papers (5)

1.

Pan-Neurodegeneration Proteomics Reveals Disease Subtypes and Molecular Signatures in Six Neurodegenerative Disorders

Number of pages: 66 Posted: 08 May 2025
St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, Mount Sinai Health System - Icahn Institute for Genomics and Multiscale Biology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Mount Sinai Health System - Icahn Institute for Genomics and Multiscale Biology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital - Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, University of Antwerp, State University of New York (SUNY) - SUNY Upstate Medical University, Rush University - Alzheimer’s Disease Center, Emory University, Emory University - Department of Biochemistry, Emory University - Department of Neurology, Mount Sinai Health System - Department of Psychiatry, Banner Health - Civin Laboratory for Neuropathology, Banner Health - Civin Laboratory for Neuropathology, Mayo Clinic - Florida - Department of Neuroscience, Mayo Clinic - Florida - Department of Neuroscience, Mayo Clinic - Florida, Mayo Clinic, University of Antwerp, University of Texas Southwestern Medical Center, St. Jude Children’s Research Hospital, Mount Sinai Health System - Department of Genetics and Genomic Sciences, St. Jude Children’s Research Hospital and Independent
Downloads 161 (477,517)

Abstract:

Loading...

Neurodegenerative diseases (NDs), proteomics, proteome, mass spectrometry, protein aggregation, Abeta (Aβ), amyloid, tau, TDP-43, α-synuclein, U1 snRNP, post-translational modifications (PTMs), phosphorylation, ubiquitination, Alzheimer's disease (AD), Lewy body dementia (LBD), frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP), vascular dementia (VAD), Parkinson’s disease (PD), progressive supranuclear palsy with tau pathology (PSP/ FTLD-tau), molecular subtypes, disease network

2.

Multi-Scale Integration of Human Brain Vascular and CSF Proteomes Reveals Biomarkers of Cerebral Amyloid Angiopathy Linked to Alzheimer’s Disease Risk

Number of pages: 75 Posted: 24 Oct 2025
Emory University, Emory University, Emory University, Rush University - Alzheimer’s Disease Center, Emory University, Emory University, Emory University, Emory University, Emory University, University of California, Davis, Emory University, Emory University, Emory University, Emory University - Department of Pathology and Laboratory Medicine, Yale University - School of Medicine, Rush University - Rush University Medical Center, The Jackson Laboratory, Rush University - Alzheimer’s Disease Center, University of Pennsylvania - Department of Pathology and Laboratory Medicine, Columbia University - Irving Medical CenterColumbia University - Center for Translational and Systems Neuroimmunology, Rush University - Alzheimer’s Disease Center, Emory University - Department of Neurology, Emory University, Emory University, Emory University, Independent, Emory University, University of California, Davis, Emory University - Department of Neurology, Emory University - Department of Biochemistry and Independent
Downloads 73 (883,195)

Abstract:

Loading...

3.

Multi-Omic Characterization of Brain Changes in the Vascular Endothelial Growth Factor Family During Aging and Alzheimer's Disease

Number of pages: 29 Posted: 07 Nov 2022
Vanderbilt University, Vanderbilt University - Medical Center, Vanderbilt University - Medical Center, Vanderbilt University - Medical Center, Columbia University - Center for Translational and Systems Neuroimmunology, Columbia University - Irving Medical CenterColumbia University - Center for Translational and Systems Neuroimmunology, Stanford Hospital, Vanderbilt University - Medical Center, Vanderbilt University - Vanderbilt Genetics Institute, Vanderbilt University - Vanderbilt Genetics Institute, Emory University - Department of Biochemistry, Vanderbilt University - Medical Center, Rush University - Alzheimer’s Disease Center, Rush University - Alzheimer’s Disease Center, Government of the United States of America - Pacific Northwest National Laboratory and Vanderbilt University - Medical Center
Downloads 57 (1,010,164)

Abstract:

Loading...

VEGF, Alzheimer's disease, proteomics, transcriptomics, cognition

4.

Mitochondrial Respiratory Chain Protein Co-Regulation in the Human Brain

Number of pages: 59 Posted: 28 Jul 2021
Columbia University Irving Medical Center - Division of Behavioral Medicine, Columbia University Irving Medical Center - Department of Physiology and Cellular Biophysics, Columbia University - Center for Translational & Computational Neuroimmunology, Columbia University Irving Medical Center - Center for Translational & Computational Neuroimmunology, Pacific Northwest National Laboratory, Emory University - Department of Neurology, Government of the United States of America - Division of Mental Health, National Institute on Aging Intramural Research Program - Clinical and Translational Neuroscience Section, Government of the United States of America - Translational Gerontology Branch, Emory University - Department of Biochemistry, Rush University - Alzheimer’s Disease Center, Columbia University - Center for Translational and Systems Neuroimmunology and Columbia University Irving Medical Center - Division of Behavioral Medicine
Downloads 40 (1,196,171)

Abstract:

Loading...

Mitochondrial respiratory chain, post-mortem brain, Alzheimer disease, proteomics, ROSMAP, BLSA, Banner

5.

Plasma Proteomic Networks Reveal Shared Biology with Brain Linked to Alzheimer’s Disease Pathology

Number of pages: 42 Posted: 11 Jul 2026
Emory University, Emory University, Emory University, Emory University, Emory University, Emory University, Emory University, Emory University, Emory University - Department of Neurology, Emory University - Department of Biochemistry and Independent
Downloads 9

Abstract:

Loading...

Alzheimer's Disease, Amyloid, Biomarkers, Cerebrospinal Fluid, Plasma, Phosphorylated Tau, Proteomics, Microbead Enrichment, Data-Independent Acquisition (DIA), Mass Spectrometry, Networks, Biomarkers