University of Cambridge - Medical Research Council Cancer Unit, University of Dundee - Jacqui Wood Cancer Centre, University of Cambridge - Medical Research Council Mitochondrial Biology Unit, University of Dundee - Centre for Gene Regulation and Expression, University of Dundee - Centre for Gene Regulation and Expression, University of Dundee - Jacqui Wood Cancer Centre, University of Dundee - Division of Cellular Medicine, University of Cambridge - Medical Research Council Cancer Unit, University of Cambridge - Medical Research Council Cancer Unit, Trinity College (Dublin) - School of Biochemistry and Immunology, University of Cambridge - Medical Research Council Cancer Unit, University of Dundee - Centre for Gene Regulation and Expression, University College London - UCL Queen Square Institute of Neurology, University of Dundee - Division of Cell Signalling, University of Cambridge - Medical Research Council Mitochondrial Biology Unit and University of Dundee - Jacqui Wood Cancer Centre