affiliation not provided to SSRN, Institute for Neuropathology - Sano Centre for Computational Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, National Institutes of Health - Laboratory of Neurogenetics, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Government of the United States of America - National Institute of Neurological Disorders and Stroke (NINDS), affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University College London - UCL Queen Square Institute of Neurology, affiliation not provided to SSRN, University College London - Department of Molecular Neuroscience, University College London - Department of Molecular Neuroscience, Harvard University - Department of Neurology and University of Zurich - Institute of Neuropathology

University of Cambridge - Medical Research Council Cancer Unit, University of Dundee - Jacqui Wood Cancer Centre, University of Cambridge - Medical Research Council Mitochondrial Biology Unit, University of Dundee - Centre for Gene Regulation and Expression, University of Dundee - Centre for Gene Regulation and Expression, University of Dundee - Jacqui Wood Cancer Centre, University of Dundee - Division of Cellular Medicine, University of Cambridge - Medical Research Council Cancer Unit, University of Cambridge - Medical Research Council Cancer Unit, Trinity College (Dublin) - School of Biochemistry and Immunology, University of Cambridge - Medical Research Council Cancer Unit, University of Dundee - Centre for Gene Regulation and Expression, University College London - UCL Queen Square Institute of Neurology, University of Dundee - Division of Cell Signalling, University of Cambridge - Medical Research Council Mitochondrial Biology Unit and University of Dundee - Jacqui Wood Cancer Centre

University of Dundee - Jacqui Wood Cancer Centre, University College London - UCL Queen Square Institute of Neurology, University of Dundee - Jacqui Wood Cancer Centre, University of Dundee - Jacqui Wood Cancer Centre, University of Dundee - Jacqui Wood Cancer Centre, University of Dundee - MRC Protein Phosphorylation and Ubiquitylation Unit, University College London - UCL Queen Square Institute of Neurology and University of Dundee - Jacqui Wood Cancer Centre