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Sarah Dimeloe

University of Birmingham - Institute of Immunology and Immunotherapy

SCHOLARLY PAPERS

4

DOWNLOADS

124

TOTAL CITATIONS

0

Scholarly Papers (4)

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1.

Canagliflozin Impairs T-Cell Effector Function via Metabolic Suppression in Autoimmunity

Number of pages: 28 Posted: 10 Aug 2022
Benjamin J. Jenkins, Julianna Blagih, Simon Eastham, David Hill, Fernando M. Ponce-Garcia, Megan M. Hanlon, Eric Ma, Emma Bishop, Caroline J. Bull, April Rees, James G. Cronin, Elizabeth C. Jury, Sarah Dimeloe, Douglas J. Veale, Catherine A. Thornton, Karen H. Vousden, David Finlay, Ursula Fearon, Linda V. Sinclair, Gareth W. Jones, Emma E. Vincent and Nick Jones
Swansea University - Institute of Life Science, The Francis Crick Institute, University of Bristol - Cellular and Molecular Medicine, University of Bristol - Cellular and Molecular Medicine, University of Bristol, Trinity College (Dublin) - Department of Molecular Rheumatology, Van Andel Institute - Department of Metabolism and Nutritional Programming, University of Birmingham - Institute of Immunology and Immunotherapy, University of Bristol - Cellular and Molecular Medicine, Swansea University - Institute of Life Science, Swansea University - Institute of Life Science, University College London - GOSH and Centre for Rheumatology Research, University of Birmingham - Institute of Immunology and Immunotherapy, University College Dublin (UCD), Swansea University - Institute of Life Science, The Francis Crick Institute, Trinity College (Dublin) - School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute - Department of Molecular Rheumatology, University of Dundee - Division of Cell Signaling and Immunology, University of Bristol - Cellular and Molecular Medicine, University of Bristol - Translational Health Sciences and Swansea University - Institute of Life Science
Downloads 54 (1,020,567)

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immunometabolism, T-cell, CD4 T-cell, gliflozins, canagliflozin, autoimmunity, human

2.

IL-7 Promotes Integrated Glucose and Amino Acid Sensing During Homeostatic CD4+ T Cell Proliferation

Number of pages: 31 Posted: 07 Aug 2024
Seema Bachoo, Nancy Gudgeon, Emma Bishop, Audrey Kelly, Alejandro Huerta-Uribe, Jordan Loeliger, Corina Frick, Oliver D.K. Maddocks, Paul Lavender, Christoph Hess, Sarah Dimeloe and Sneak Peek Administrator
University of Birmingham, University of Birmingham, University of Birmingham, King’s College London, University of Glasgow, University of Basel, University of Basel, University of Glasgow, King's College London - MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, University of Basel, University of Birmingham - Institute of Immunology and Immunotherapy and Independent
Downloads 27 (1,372,601)

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T lymphocyte, T cell, Proliferation, Metabolism, IL-7, mTOR, Nutrient Sensing

3.

Succinate Uptake by T Cells Suppresses Their Anti-Tumour Function Via Inhibition of Mitochondrial Glucose Oxidation

Number of pages: 24 Posted: 22 Dec 2021
Nancy Gudgeon, Haydn Munford, Emma Bishop, James Hill, Taylor Fulton-Ward, David Bending, Jennie Roberts, Daniel Tennant and Sarah Dimeloe
University of Birmingham, University of Birmingham, University of Birmingham - Institute of Immunology and Immunotherapy, University of Birmingham, University of Birmingham, University of Birmingham, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham and University of Birmingham - Institute of Immunology and Immunotherapy
Downloads 27 (1,359,097)

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T cell, Metabolism, Metabolite, succinate, Tumour microenvironment

4.

Succinate Is an Anaplerotic TCA Cycle Substrate for Malignant Plasma Cells in Multiple Myeloma, Supporting Proliferation

Number of pages: 25 Posted: 30 Mar 2026
Nancy Gudgeon, Taylor Fulton-Ward, Victoria Stavrou, Aidan Haslam, Graham McIlroy, Hannah Giles, Guy Pratt and Sarah Dimeloe
University of Birmingham, University of Birmingham, University of Birmingham, University Hospitals Birmingham NHS Foundation Trust, University Hospitals Birmingham NHS Foundation Trust, University Hospitals Birmingham NHS Foundation Trust, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham - Institute of Immunology and Immunotherapy
Downloads 16 (1,509,872)

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Multiple myeloma, metabolism, bone marrow microenvironment, cancer metabolism, TCA cycle